Study of the bacteriological profile of neonatal septicemia and associated risk factors
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 3
Abstract
Introduction Neonatal sepsis is one of the major causes of morbidity and mortality among the newborns in the developing countries For the effective management of neonatal sepsis knowledge about causative agent and antibiotic sensitivity pattern play a vital role Present study was undertaken to analyze the various risk factors of bacterial sepsis to isolate aerobic bacteria causing neonatal septicemia and to study the antibiogram of bacterial isolatesMaterial and Methods Study was done over a period of one year 198 clinically suspected cases of neonatal septicemia were included in the study Detailed record of various predisposing neonatal factors were noted in a proforma Blood samples from the neonates were subjected to aerobic blood cultures The identification of the causative organism was carried out by standard identification tests and antibiotic sensitivity testing was done as per Clinical and Laboratory Standards Institute guidelinesResults Of 198 neonates studied predisposing factors for neonatal sepsis were mainly low birthweight and preterm Blood cultures were positive in 1286464 cases Predominant organisms isolated were Staphylococcus aureus 547 and Klebsiella spp 141 Among Staphylococcus aureus 436142 isolates were MRSA and most of them were sensitive only to vancomycin and linezolid Most of the MSSA were sensitive to cotrimoxazole clindamycin ciprofloxacin vancomycin linezolid Most of the Gram negative bacilli were sensitive to imipenem piperacillintazobactam and amikacinConclusion For the effective management of neonatal sepsis continued surveillance is mandatory for each center due to temporal changes in the causative organisms and their antibiotic susceptibilityKeywords Bacteriological Profile Neonatal Septicemia Risk Factors Antibiogram and Blood Culture
Authors and Affiliations
Vedavati B. I. , Amrutha Kumari B
Keywords
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- EP ID EP485860
- DOI 10.18231/2581-4761.2018.0029
- Views 93
- Downloads 0
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