Study of Uropathogens among Type II Diabetic Patients and Their Amtimicrobial Resistance Pattern among Rural South Indian Population
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
Infection of the urinary tract (UTI) is among the most frequent infectious diseases in humans. Urinary tract infection is also a most common infection among the diabetic patients. The aim of our study is to know the prevalence of various uropathogens among long term Type II Diabetic patients and to reveal their corresponding antimicrobial resistance pattern. Urine samples were collected from randomly selected 260 diabetic patients who suffered from urinary tract infection. Urine cultures were done by standardised method . Urine samples were inoculated onto Blood agar and MacConkey agar and colonies identified using appropriate biochemical methods. Data was analyzed statistically. The results of our study showed that females (71%) are more prone to pathogenic urinary tract infection than males (43%). In terms of pathogenic distribution, Escherchia coli (54%), Klebsiella (21%), Pseudomonas (12%), Proteus (4%), Acinetobacter (1%), Staphylococcus aureus (14%), Enterococci (1%) and Coagulase negative Staphylococcus auerus CoNS (8%) were common among the diabetic patients. The overall prevalence of urinary tract infection was 58%. Our result revealed that there was significant growth bacteriuria in 152 patients. High level resistance is seen to Cotrimoxazole, Ciprofloxacin, Ceftazidime and Cefipime. Sensitivity of Nitrofurantoin to Pseudomonas and Acinetobacter were not tested as they have intrinsic resistance to that drug. Amikacin is found to be very effective against all the isolates. Most of the isolates were sensitive to Imepenem.
Authors and Affiliations
Dhandapany Senthil Pragash, Smiline Girija, Usha Shekar, Vijaya Rayapu, Malathi .
Keywords
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