Study on Use of Intramuscular Tramadol as Analgesic during Labour
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 4
Abstract
The aim of study is to study the use of intramuscular tramadol as analgesic during labor. Prospective observational study conducted in a total of 51 patients, enrolled from labor ward of obstetrics and gynaecology of RMMCH who are in labor and administered with 100mg intramuscular tramadol as analgesic and with no other complications. The following points were observed to assess the safety and efficacy of intramuscular tramadol as analgesic during labor, they are:[1] age wise distribution of subjects, [2] demographic profile of parturient women, [3] onset of analgesic activity, [4] extent of pain relief using McGill’s score, [5] evaluation of APGAR score to assess the impact of analgesic effect on foetus, [6] quantum of use of tramadol as Defined Daily Dose (DDD) [7] identification and documentation of adverse effects, if any. In our study majority of the subjects were in age group 24-29 with mean gestational age 36±2.25 weeks. Systolic and diastolic blood pressure of all subjects is within the normal range. 63% of cases shows onset of action within 16-20 minutes. APGAR scores was in between 4-6 at one minute and 7-9 at five minutes. APGAR score was less than 4 in five babies at one minute and the number reduced to one after 5 minutes. The quantum of use of tramadol as DDD is higher than the assigned DDD. Incidence of ADR observed is 5.8%. Most of the patients experienced discomforting and distressing pain and none experienced horrible and excruciating pain on 100mg intramuscular dose of Tramadol.Our study suggests that therapeutic dose of tramadol intramuscular can be recommended as labour analgesia. It is simple to use and causes significant pain relief with minimal side effects.
Authors and Affiliations
Akshay Kumar Andey, Aleenasibi . , Ullagantisaichaitanya . , Guru Prasad Mohanta M. Pharm, M. Sangeereni M. D
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