SYNTHESIS, CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY OF NOVEL N-SUBSTITUTED-5-OXA-IMIDAZOLE
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Various substituted 2-(2'-phenyl-4'-p-dimethylaminobenzylidenyl imidazolin-5'-one)-6-fluoro-7- substituted (1,3) benzothiazoles and 2-(2'-phenyl-4'-o-hydroxy benzylidenyl-5'oxo imidazolin-1-yl amino) - 6-fluoro-7-substituted (1,3) benzothiazoles containing different functional groups have been synthesized by treating substituted 2-aminobenzothiazoles with oxozolone in presence of dry pyrirdine. The identity of compounds were confirmed on the basis of their spectral (UV-Visible, IR, 1H NMR and Mass) data. Further, they have been screened for their antimicrobial, antiinflammatory, anticonvulsant and anthelmintic activities.
Authors and Affiliations
Shameer H, Nageswara Rao R, Vijay Kumar MMJ, Jayachandran E, Sreenivasa GM
Keywords
Related Articles
- EP ID EP33025
- DOI -
- Views 361
- Downloads 0
Isolation and identification of Azospirillum isolates from different paddy fields of North Bengal
Samples of rhizosphere soil, non-rhizosphere soil and roots of rice plants were collected from the particular locations of the 3 districts (Bogra, Naowgaon and Dinajpur) of North Bengal. Twenty different colonies of Az...
Comparative study of Stylosanthes fruticosa & Indigofera linnae for anthelmintic activity
The present study aimed at the in-vitro evaluation of anthelmintic activity of aqueous, hydroalcoholic, alcoholic and hot continuous methanolic sohxalet extracts of whole plants of Stylosanthes fruticosa & Indigofera li...
SIMULTANEOUS ESTIMATION OF OLMESARTAN AND ATORVASTATIN IN BULK AND FROMULATION BY USING UV SPECTROSCOPY AND RP-HPLC
Simple, rapid and accurate UV Spectroscopic (Simultaneous Equation method and First order derivative method) and an isocratic RP – HPLC methods showed excellent sensitivity, reproducibility, accuracy, and repeatability...
Acute and sub-acute toxicity studies of Actaea acuminata H. Hara roots
Actaea acuminata (Wall. ex Royle) H. Hara (Himalayan Baneberry; Ranunculaceae) has been traditionally used in the treatment of various ailments especially in CNS related diseases. A survey of literature revealed that n...
Investigation of Oxygen absorbent in food packages
Active packaging is one of the newest concepts in food packages uses in order to supply the customer demands in shortest time. To prepare targeted foods, globalization of food market, transferring to longer distances,...