SYNTHESIS, CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY OF NOVEL N-SUBSTITUTED-5-OXA-IMIDAZOLE
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Various substituted 2-(2'-phenyl-4'-p-dimethylaminobenzylidenyl imidazolin-5'-one)-6-fluoro-7- substituted (1,3) benzothiazoles and 2-(2'-phenyl-4'-o-hydroxy benzylidenyl-5'oxo imidazolin-1-yl amino) - 6-fluoro-7-substituted (1,3) benzothiazoles containing different functional groups have been synthesized by treating substituted 2-aminobenzothiazoles with oxozolone in presence of dry pyrirdine. The identity of compounds were confirmed on the basis of their spectral (UV-Visible, IR, 1H NMR and Mass) data. Further, they have been screened for their antimicrobial, antiinflammatory, anticonvulsant and anthelmintic activities.
Authors and Affiliations
Shameer H, Nageswara Rao R, Vijay Kumar MMJ, Jayachandran E, Sreenivasa GM
Keywords
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