THE BENEFICIAL EFFECT OF 20% SUNFLOWER SEED OIL CREAM ON MILD ATOPIC DERMATITIS IN CHILDREN
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 2
Abstract
Objective: The objective of this study was to evaluate the beneficial effect of topical applications of 20% sunflower seed oil (SSO) in decreasing the transepidermal water loss (TEWL) and scoring of atopic dermatitis (SCORAD) index value in mild atopic dermatitis (AD) pediatric patients in Bandung, Indonesia. Methods: This was a randomized study involving 20 children with mild AD (SCORAD<25) in Bandung, Indonesia. They were divided into 2 groups: the experimental group treated with 20% SSO cream and the control group treated with a common moisturizing cream for four weeks. The TEWL score including SCORAD index was evaluated at baseline, week 1, week 2, and week 4. Results: A total of 20 participants completed the study. In the first week, the control group had TEWL score decrement by 36.62% while the experimental group by 28.89% (p=0.88). In the fourth week, the TEWL decrements of the experimental and control group were by 56.94% and 52.50%, respectively (p=0.20), and this was followed by an improvement of SCORAD index in both treatment groups. Conclusion: The 20% SSO cream has a beneficial effect in decreasing the TEWL score and improving SCORAD indices. Therefore, it can be considered as an alternative treatment for mild AD among children.
Authors and Affiliations
Reiva Farah Dwiyana, Hartati Purbo Darmadji, Risa Miliawati Nurul Hidayah, Fitra Hergyana, Srie Prihiantini Gondokaryono, Inne Arline Diana, Catherina Jessica Sutantoyo, Hendra Gunawan
Keywords
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- EP ID EP566044
- DOI 10.22159/ijpps.2019v11i2.30707
- Views 60
- Downloads 0
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