The Effect of Gold Nanoparticles on Electrical Impedance of Tissue on Low Frequency Ranges
Journal Title: Journal of Biomedical Physics and Engineering - Year 2018, Vol 8, Issue 3
Abstract
Introduction: Electrical impedance of tissues on low frequencies includes useful information about functional and structural changes in tissues. This property is used in Electrical Impedance Tomography (EIT) imaging modality for the detection of lesions in tissues. Objective: The goal of this article is to study changes in electrical impedance of tissues in the presence of gold nanoparticles. Materials and Methods: Spherical gold nanoparticles with size of 20- 25 nm were synthesized with Turkevich method. Size distribution and shape of nanoparticles were characterized by transmission electron microscopy (TEM). Electrical impedance of two types of phantoms (chicken fat and muscle paste tissues) was measured by 4-electrode method with and without gold nanoparticles. Results: Results demonstrate a reduction in electrical impedance of tissues in the presence of gold nanoparticles. However, this reduction is not the same for fat and muscle tissues. Reductions in resistive impedance are 40.24 1.93 Ω Ω and for fat and muscle tissues on the frequency of 1 KHz, respectively. A reduction in electrical impedance is accompanied by a rise in electrical conductance leading to increase in EIT signal. Conclusion: As signal enhancement is different for fat and muscle tissues; presence of gold nanoparticles could be used to improve EIT image contrast.
Authors and Affiliations
M. Ostovari, N. Riahi Alam, M. M. Gharibvand
Keywords
Related Articles
- EP ID EP455524
- DOI -
- Views 105
- Downloads 0
Why Should We Have a Periodic Safety and Performance Program for Medical Devices
Nowadays, more than 10,000 different types of medical devices can be found in hospitals.These devices used in medical centers and hospitals for monitoring and treatment of patients require periodic safety and performance...
Evaluation of Breast Cancer Radiation Therapy Techniques in Outfield Organs of Rando Phantom with Thermoluminescence Dosimeter
Background: Given the importance of scattered and low doses in secondary cancer caused by radiation treatment, the point dose of critical organs, which were not subjected to radiation treatment in breast cancer radiother...
Design and Production of Two-piece Thyroid-neck Phantom by the Concurrent Use of Epoxy Resin and Poly(methyl methacrylate) Soft Tissue Equivalent Materials
The aim of this report is to present a new two-piece thyroid-neck phantom produced by the concurrent use of epoxy resin and poly(methyl methacrylate) (PMMA: plexiglass) soft tissue equivalent materials. Accordingly, mass...
The Optimization of Magnetic Resonance Imaging Pulse Sequences in Order to Better Detection of Multiple Sclerosis Plaques
Background and Objective: Magnetic resonance imaging (MRI) is the most sensitive technique to detect multiple sclerosis (MS) plaques in central nervous system. In some cases, patients who were suspicious of having MS wh...
Online Estimation of Elbow Joint Angle Using Upper Arm Acceleration: A Movement Partitioning Approach
Estimating the elbow angle using shoulder data is very important and valuable in Functional Electrical Stimulation (FES) systems which can be useful in assisting C5/C6 SCI patients. Much research has been conducted based...