THE ROLE OF BLOOD COAGULATION FACTORS AND HYPERURICEMIA IN THE DEVELOPMENT OF CARDIOVASCULAR EVENTS IN PATIENTS WITH OSTEOARTRITIS
Journal Title: INTERNATIONAL ACADEMY JOURNAL "Web of Scholar" - Year 2017, Vol 1, Issue 7
Abstract
Inflammation plays an important role in the pathogenesis of osteoarthritis. The study of blood coagulation markers (number of platelets, mean platelet volume, fibrinogen, D-dimer, antithrombin ІІІ, C-reactive protein, uric acid) was conducted in patients with osteoarthritis in combination with hyperuricemia and its ability to increase the risk of negative cardiovascular events. This study included 50 patients (40 men and 10 women) suffering from osteoarthritis of the knee joints. The average age of patients was 59.5±3.6 years. Patients were divided into 3 groups: group 1 – patients with osteoarthritis; group 2 – patients with osteoarthritis in combination with hyperuricemia; group 3 – control group of practically healthy patients. In patients with osteoarthritis in combination with hyperuricemia, the above-described indicators contribute to an increased risk of development of negative cardiovascular events. Therefore, there is a need for monitoring these indicators in this group of patients.
Authors and Affiliations
A. P. Kuzmina, O. M. Lazarenko, М. І. Arapu
Keywords
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