The study of anti-diabetic activity of aqueous extract of root of Gynandropsis gynandra in diabetic rats
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 1
Abstract
It has been planned to explore the hypoglycaemic and antihyperglycaemic activity of aqueous extract of root of Gynandropsis gynandra herb in normal and diabetic rats.The extract was evaluated for its specific physical and chemical characteristics in order to standardize it. The aqueous extract of root of G.gynandra were tested at 3 dose levels (100, 200 and 400 mg/kg each) in rats. In each case the initial test was performed at dose of 100 mg/kg. The actions were compared with standard Tolbutamide drug at a dose of 40 mg/kg. The data obtained was analysed with the oneway analysis of variance (ANOVA), followed by a post hoc of Dunnett’s T-test. The study revealed that the Gynandropsis gynandra herb was found to have hypoglycemic actions compared with Tolbutamide.
Authors and Affiliations
Y. Trilochana, Dasi Jeevan Mani Babu, P. Rajeswara Rao
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