To Assess the Levels of Lipid Profile, Uric Acid, Albumin / Globulin Ratio and Trace Elements in the Serum of Psoriasis Patients
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Psoriasis is a chronic, autoimmune disease that appears when the immune system sends out faulty signals which leads to speeding up the growth cycle of skin cells. Study was done to access the biochemical analytes like lipid profile, uric acid, A/G Ratio, serum electrolytes in psoriatic patients. Material and Methods: Study was done from November 2016 to October 2017 in RVM Medical College and the subjects were taken from the department of Dermatology. Patients with plaque psoriasis of age group 20 years – 60 years without any history of topical or systemic drug therapy and without any coexisting disease were selected for the study. The subjects for control group were taken from healthy paramedical staff, volunteers and patients attending skin outpatient department. Results: The mean±SD of serum total cholesterol, triglycerides, VLDL, LDL, serum uric acid in the study group showed a significant increase when compared to that of the controls. But the mean±SD of serum HDL was lower in the study group when compared to the controls. The mean ratio of Na+/ K+ and Total Cholesterol/ HDL in the study group showed a significant increase compared to the control population. The mean ratio of Ca2+/Mg2+ and HDL/LDL in the study group showed a significant decrease compared to the control population. Conclusion: Psoriasis is a chronic, auto-immune disease which should be treated with ultimate care to reduce the exacerbations especially in winter season. Regular follow-ups along with estimation of routine and special biochemical parameters will reduce the risk of cardiovascular complications.
Authors and Affiliations
Pratyusha . , Sashidhar Reddy. B, Sangeeth .
Keywords
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