Transfusion adverse events in a tertiary hospital from 2016 to 2022: a retrospective analysis
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 7
Abstract
Objective To strengthen the management of transfusion adverse events, so as to reduce the occurrence of medical damage and accidents, and guarantee the safety of blood transfusion. Methods The adverse events of blood transfusion reported in our hospital from July 2016 to December 2022 were collected, the reasons were tracked, and continuous improvements were made. Results From 2016 to 2022, a total of 315 transfusion adverse events were reported, including 233(73.97%, 233/315) cases of transfusion reactions and 82(26.03%, 82/315) transfusion adverse events. There were 271 328 transfusion cases in the same period, and the incidence of transfusion reactions was 0.858 7‰(233/271 328). The number of transfusion application was 129 887, and the incidence of transfusion adverse event is 0.631 3‰(82/129 887). Sixty-eigtht(82.93%, 68/82) cases of transfusion adverse events were caused by human factors, while the other 14(17.07%, 14/82) cases were non-human factors. According to the linear regression analysis, we have concluded that the year is a significant indicator for transfusion reaction rates (P<0.05), but not for transfusion adverse event rates (P>0.05). Conclusion Strengthening the management of reporting adverse events in clinical blood transfusion, monitoring the incidence, analyzing and improving different types of adverse events by management tools can reduce the medical risks of blood transfusion and help to guarantee the safety of clinical blood transfusion.
Authors and Affiliations
Yachun SUN, Leiping WANG, Guihua DENG, Xinyan LONG, Shunling YUAN, Qingbao MENG
Diagnosis and treatment of passenger lymphocyte syndrome following secondary ABO-incompatible allogeneic hematopoietic stem cell transplantation
Objective To investigate the clinical characteristics and diagnosis and treatment of passenger lymphocyte syndrome (PLS) in patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methods A tot...
Correlation of D-dimer, serum potassium and thromboelasto-graphy parameters with progressive hemorrhagic injury
Objective To investigate the correlation between D-dimer, serum potassium and thromboelastography parameters and progressive hemorrhagic injury (PHI) after brain injury. Methods The data of 209 patients with traumatic br...
The clinical serological characterization of cisAB and B(A) blood groups
Objective To determine the rare ABO blood subgroups rapidly and ensure the blood transfusion safety of five patients by a series of serological tests and family investigation, as their preliminary serological results of...
Analysis of HLA allele-specific antibodies and Eplets in patients with platelet transfusion refractoriness
Objective To analyze the specificity and Eplets of HLA allele-specific antibody in patients with platelet transfusion refractoriness (PTR). Methods HLA-A and B genotypes were detected by PCR-SBT, and HLA-Ⅰ antibodies in...
Changes in perioperative blood group antibody of 33 type-A/B recipients in ABO-incompatible kidney transplantation
Objective To statistically analyze the perioperative results of patients with ABO-incompatible kidney transplantation (ABOi-KT), in order to explore the changes in blood group antibody of type-A/B recipients. Methods A t...