Use of positron emission tomography in patients with gallbladder carcinoma and cholangiocarcinoma
Journal Title: Gastroenterologia Polska - Year 2007, Vol 14, Issue 5
Abstract
Conventional imaging techniques such as ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI) are useful in detecting gallbladder and bile ductsabnormalities but are not always able to differentiate malignancy from other benign disease processes. Positron emission tomography (PET) by use of 18-F-fluorodeoxyglucose (FDG) is one of the most modern methods of obtaining a functional image of thehuman body or selected organs.The basis of this method is significanty increased FDG metabolism in the malignant neoplasm cells. The combination of the PET with CT improve the diagnosti ccapability of this method. PET is highly accurate for detection of the primary biliary tract tumor. It is particularly useful when other imaging techniques are equivocal. Inclusion of the PET imaging into the diagnostic process in case of gallbladder cancer and cholangiocarcinoma improves the efficiency in diagnosis of distantmetastases and detection of recurrence. PET/CT is particularly valuable in detecting unsuspected distantmetastases which are not diagnosed by conventional imaging.The results of PET study can change the stage of disease changing the way of treatment in some patients. PET is not suitable for detection of regional lymph node metastases and carcinomatosis. PET and PET/CT imaging must be interpreted carefully in patients with primary sclerosis cholangitis, biliary stents or other inflammatory conditions. PET/CT image should find wider use in patients with biliary tract carcinoma as a new complementary method of the other diagnostic examination.
Authors and Affiliations
Zbigniew Kula
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