Vitamin D Administration: Intramuscular versus oral route: Comparisonof Effectiveness
Journal Title: Scholars Academic Journal of Pharmacy - Year 2017, Vol 6, Issue 5
Abstract
Vitamin D is afat soluble vitamin essential for bone health. Its deficiency is highly prevalent all over the world without adequate steps or efforts to solve this problem.The aim of the study is to compare the effectiveness of orally administered versus intramuscularlyadministered vitamin D preparation.Sixty patients with Hypovitaminosis D participated in the study. Thirty of them (50%) preferred the oral route for taking vitamin D while the other 30patient (50%)chose the intramuscular(I.M) injection route. Both groups used the same preparation.Two weeks later vitamin D serum level was re-checked, and a comparison of the results of the two groups was recorded.The serum level of vitamin D after (I.M) administration showed marked increment compared with results after oral way despite using the samedose in both routes, although both routs cause a significant increment .The study concluded thatI.M administration of vitamin D increased its serum level more effectively than the oral route of the same dose. Keywords:25(OH) vitaminD, Hypovitaminosis D, oral route and intramuscular route.
Authors and Affiliations
Al-Hilali K. A, Al-Anbari H. H, Clinical Pharmacology
Keywords
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