WISTAR RATS’ BEHAVIORAL RESPONSES IN REMOTE PERIOD AFTER INTRAUTERINE EXPOSURE 131I
Journal Title: Наукові праці. Серія "Техногенна безпека" - Year 2016, Vol 280, Issue 268
Abstract
In numerous clinical and experimental studies have found exceptional radiosensitivity of the nervous system develops, according to the study of acute and long-term effects of ionizing radiation (gamma, neutron or x-ray). When radiation accident at the nuclear reactor is in particular the release into the environment of radioisotopes of iodine are short of uranium fission products and transuranic elements are the most biologically significant, particularly 131I. Experimental studies to determine the effects of prenatal exposure on the brain 131I do not conducted. A study of behavioral reactions in rats Wistar male that suffered prenatal exposure due to a single injection of 131I radionuclide activity with the activity of 27,35 kBq 12–14 th day gestational period in the late period of observation – in 8–10 months after exposure. Research results in an open field tests, raised cross-shaped maze, black and white cameras allow the conclusion to increase the level of research activity, but no significant changes in the level of anxiety of animals exposed to 131I in utero. Study of cognitive status of animals using passive avoidance test not identified significant differences between the performance behavior of animals in the control and experimental groups under the conditions of the experiment.
Authors and Affiliations
Ye. Tukalenko, I. Tubaltseva, A. Lypska
Keywords
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