Preparation and ocular pharmacokinetics of ganciclovir liposomes Journal title: The AAPS Journal Authors: Yan Shen, Jiasheng Tu Subject(s): Medicine
Pharmacokinetics in mice implanted with xenografted tumors after intravenous administration of tasidotin (ILX651) or its carboxylate metabolite Journal title: The AAPS Journal Authors: Peter L. Bonate, David Beyerlein, Jennifer Crawford, Stephanie Roth, Roy Krumbholz, Steve Schmid Subject(s): Medicine
Opioid Tolerance Development: A Pharmacokinetic/Pharmacodynamic Perspective Journal title: The AAPS Journal Authors: Emily O. Dumas, Gary M. Pollack Subject(s): Medicine
Concepts and Challenges in Quantitative Pharmacology and Model-Based Drug Development Journal title: The AAPS Journal Authors: Liping Zhang, Marc Pfister, Bernd Meibohm Subject(s): Medicine
The pharmacokinetics of escitalopram in patients with hepatic impairment Journal title: The AAPS Journal Authors: Johan Areberg, Jacob Strøyer Christophersen, Mette Nøhr Poulsen, Frank Larsen, Karl-... Subject(s): Medicine
Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies Journal title: The AAPS Journal Authors: Mark G. LeSage, Daniel E. Keyler, Paul R. Pentel Subject(s): Medicine
Making the Most of Clinical Data: Reviewing the Role of Pharmacokinetic-Pharmacodynamic Models of Anti-malarial Drugs Journal title: The AAPS Journal Authors: Julie A. Simpson, Sophie Zaloumis, Alysha M. DeLivera, Ric N. Price, James M McCaw Subject(s): Medicine
A Mechanistic Pharmacokinetic Model Elucidating the Disposition of Trastuzumab Emtansine (T-DM1), an Antibody–Drug Conjugate (ADC) for Treatment of Metastatic Breast Cancer Journal title: The AAPS Journal Authors: Brendan Bender, Douglas D. Leipold, Keyang Xu, Ben-Quan Shen, Jay Tibbitts, Lena E. Friberg Subject(s): Medicine
Population Pharmacokinetic Modeling of LY2189102 after Multiple Intravenous and Subcutaneous Administrations Journal title: The AAPS Journal Authors: Sébastien Bihorel, Jill Fiedler-Kelly, Elizabeth Ludwig, Joanne Sloan-Lancaster, Eyas Raddad Subject(s): Medicine
Application of a Physiologically Based Pharmacokinetic Model Informed by a Top-Down Approach for the Prediction of Pharmacokinetics in Chronic Kidney Disease Patients Journal title: The AAPS Journal Authors: Hiroyuki Sayama, Hiroaki Takubo, Hiroshi Komura, Motohiro Kogayu, Masahiro Iwaki Subject(s): Medicine
Physiologically Based Absorption Modelling to Predict the Impact of Drug Properties on Pharmacokinetics of Bitopertin Journal title: The AAPS Journal Authors: Neil Parrott, Dominik Hainzl, Emmanuel Scheubel, Siegfried Krimmer, Christophe Boetsch, Elena Guerin... Subject(s): Medicine
Simulation of Monoclonal Antibody Pharmacokinetics in HumansUsing a Minimal Physiologically Based Model Journal title: The AAPS Journal Authors: Linzhong Li, Iain Gardner, Miroslav Dostalek, Masoud Jamei Subject(s): Medicine
Changes in Individual Drug-Independent System Parameters during Virtual Paediatric Pharmacokinetic Trials: Introducing Time-Varying Physiology into a Paediatric PBPK Model Journal title: The AAPS Journal Authors: Khaled Abduljalil, Masoud Jamei, Amin Rostami-Hodjegan, Trevor N. Johnson Subject(s): Medicine
A White Paper—Consensus and Recommendations of a Global Harmonization Team on Assessing the Impact of Immunogenicity on Pharmacokinetic Measurements Journal title: The AAPS Journal Authors: J. M. Sailstad, L. Amaravadi, A. Clements-Egan, B. Gorovits, H. A. Myler, R. C. Pillutla, S. Pursuho... Subject(s): Medicine
Practical Considerations for Dose Selection in Pediatric Patients to Ensure Target Exposure Requirements Journal title: The AAPS Journal Authors: April M. Barbour, Michael J. Fossler, Jeffrey Barrett Subject(s): Medicine
