5 A COMPARATIVE STUDY OF INTRATHECAL CLONIDINE WITH DEXMEDETOMIDINE IN LOWER ABDOMINAL AND LOWER LIMB SURGERIES
Journal Title: Indian journal of applied basic medical sciences - Year 2015, Vol 17, Issue 24
Abstract
Introduction and objectives:Present study was designed to evaluate Efficacy of two different α2 agonists Clonidine (45 µg) and DXM(5µg) as a adjuvant to intrathecal Hyperbaric Bupivacaine 0.5%.Aims & objectives of study:toCompare the onset of sensory and motor block.Compare the duration of sensory and motor block. Assess the duration of effective postop analgesia.Compare haemodynamic changes.Observe adverse effects. Material &Methods: We have given spinal anaesthesia for lower abdominal & lower limb surgeries with clonidine &DXM as adjuvant.Observation:Both clonidine & DXM delays sensory& motor onset, prolongs duration of sensory& motor analgesia, and postoperative analgesia as compare to Bupivacaine group with minimum haemodynamic changes.CONCLUSION :Both clonidine & DXM can be used as adjuvant to bupivacaine for prolonged analgesia.
Authors and Affiliations
DR. AMIT CHANDAK, Dr. Manisha S Kapdi
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