A Review: Physical Penetration Enhancers For Transdermal Drug Delivery Systems
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 1
Abstract
Delivery of the drug via skin would provide a useful alternative to oral route and important site of drug application for local and systemic effects with minimum undesirable side effects. Skin penetration techniques have been developed to improve bioavailability and enhance the range of drugs for which transdermal delivery is a viable option. The permeation of drug through skin can be enhanced by chemical penetration enhancers. The present review article includes the classification of permeation enhancers and their mechanism of action; thus it will help in the selection of suitable penetration enhancer for improving the permeation of poorly absorbed drugs via transdermal route.
Authors and Affiliations
Himanshi Tanwar*
The Innate Differences in the Adipocyte Membrane Fatty Acid Composition Could Be Modified By Dietary Fats in Obese Mice
Obesity-related insulin resistance is the risk factor for developing type 2 diabetes mellitus. The fatty acid composition of plasma membrane is known as a mediator to affect insulin action. This study aimed to investigat...
Phytochemical, Proximate and Antifungal Studies on Phoenix dactylifera L
: Date fruits are one of the very common fruits known to man having a lot of vitamins and minerals necessary for the wellbeing of an individual. In this study, the aqueous, ethanolic, n-hexane and diethylether extracts o...
Fungal Profile of Occular Infection in Patients Attending In a Tertiary Care Hospital
Aim and objective: To identify the fungal etiology of Ocular infections in patients attending Ophthalmology department from the period Nov 2010 to Sep 2011 at Navodaya Medical College Hospital and Research Centre, Raichu...
Mycelial and Pigmentation studies of Dibenzothiophene desulfurizing Streptomyces species isolated from oil contaminated sites
The present work is the part of study on Dibenzothiophene (DBT) desulfurizing actinobacteria viz., Streptomyces sp. VUR PPR 101 and Streptomyces sp. VUR PPR 102 isolated from oil contaminated sites of mechanical workshop...
Identification of lead molecules with anti-hepatitis B activity in Bacopa monnieri (L.) Wettst. and Cassia fistula L. through in silico method
Chronic hepatitis B virus infection is one of the leading causes of liver cancer. In the present investigation, the anti-hepatitis B virus activity of two plants viz. Bacopa monnieri (L.) Wettst. and Cassia fistula L. we...