A Review: Physical Penetration Enhancers For Transdermal Drug Delivery Systems
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 1
Abstract
Delivery of the drug via skin would provide a useful alternative to oral route and important site of drug application for local and systemic effects with minimum undesirable side effects. Skin penetration techniques have been developed to improve bioavailability and enhance the range of drugs for which transdermal delivery is a viable option. The permeation of drug through skin can be enhanced by chemical penetration enhancers. The present review article includes the classification of permeation enhancers and their mechanism of action; thus it will help in the selection of suitable penetration enhancer for improving the permeation of poorly absorbed drugs via transdermal route.
Authors and Affiliations
Himanshi Tanwar*
Keywords
Related Articles
- EP ID EP383272
- DOI 10.9790/3008-1111101105 .
- Views 131
- Downloads 0
Pattern, Knowledge And Other Contextual Correlates Of Use Of Pain-Killers Among Students Of Niger Delta University
Pain, a ubiquitous symptom in the clinics, requires the use of analgesics to manage. Analgesics have been reported to be very widely used and abused set of drugs globally. This study was aimed at evaluating the patterns...
Design And Characterisation Of Pulsatile Capsule Device For Flurbiprofen Using Natural Excipients
The objective of the present study was to design and characterize pulsatile capsule device for Flurbiprofen using natural excipients. The Flurbiprofen fast disintegrating tablets (FDT) were formulated using superdisinteg...
Stephania glabra (Menispermaceae)- Phytochemical Perspective.
Background- Stephania glabra (Roxb) has long been used for the treatment of asthma with several other valuable uses. Over 150 alkaloids together with Flavonoids lignans, steroids, Terpenoids and coumarins have been ident...
Profile of the variation of the Serum albumin and albuminuria in type 2 diabetes in the Democratic Republic of Congo
Introduction: Kidney failure is a serious complication of diabetes type 2. The presence of albumin in urine is an important marker that should alert on kidney disease. The first detectable manifestation of diabetic nephr...
Synthesis and Cytotoxicity of Novel Analogues of Podophyllotoxin
We have synthesized four novel derivatives of podophyllotoxin, the chalcone derivatives namely 2- benzylidene-6,7-dimethoxy-4-phenyl-3,4-dihydro-2H-naphthalen-1-one (4a), 2-benzylidene-5,7-dichloro-6- hydroxy-4-phenyl-3,...