Analysis of Liver Biopsies in Children- A Histopathological Study
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 7
Abstract
Background: Liver disease in pediatrics is one of the most significant causes of morbidity and mortality in this age group. The present study was aimed at determining different pattern of liver needle biopsy in children. Materials & Methods: The present study was conducted in the department of Pathology. It included 382 liver biopsies of children of both gender. In all patients liver biopsies were evaluated. Results: Out of 382 patients, males were 202 and females were 180. The difference was non- significant (P-0.13). Age group 1month- 1 year had 190 patients, 2-5 years had 85 patients, 6-10 years had 65 patients and >11 years had 42 patients. The difference was significant (P-0.01). Common liver diseases in children were biliary tract atresia (110) followed by chronic hepatitis (92), steatosis (73), neonatal hepatitis (41), cirrhosis (38), metabolic disease (12), granulomatous hepatitis (8), CMV infection (5) and histiocytosis (3). The difference was significant (P-0.01). Conclusion: Liver biopsy is useful and informative diagnostic tool in cases of children liver diseases. Common findings were hepatitis, steatosis, CMV infection etc.
Authors and Affiliations
Jay Prakash
Keywords
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