ASSESSMENT OF IN VITRO ANTI-OXIDANT AND ANTI-MICROBIAL EFFICIENCIES OF ENDANGERED MEDICINAL PLANT FICUS DALHOUSIAE MIQ.
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2015, Vol 6, Issue 6
Abstract
Ficus dalhousiae Miq, is sparely populated endangered plant of Nilagiri hills and eastern ghats of India. It was reported to have prominent medicinal activities in the traditional medicinal system. The successive soxhlet extraction method was carried out using Hexane, Acetone, Methanol and Aqueous solvents. The quantitative estimation of total phenol content was 94µg GAE/µg by folin ciocalteu method. The antimicrobial activity was moderate and dose dependent. Polarity of the solvent was directly proportional to the zone of inhibition. Antioxidant activity of the four extracts was calculated and their IC50 values were compared with the standard ascorbic acid. Methanol extract was found to have 91.36 µg/ml inhibitory concentrations. The IC50 values were significantly increased for the four extracts and the percentage of inhibition was directly proportional to the concentration of the extract. Methanol extract has the effective antimicrobial activity and antioxidant activity.
Authors and Affiliations
Suman DSD, Narendra K, Satya M, Rathnakar KVN, Venkata G, Krishna A
Keywords
Related Articles
- EP ID EP105944
- DOI 10.7897/2230-8407.06675
- Views 72
- Downloads 0
STEM CELL TRANSPLANTATION FOR THE TREATMENT OF CANCER: A REVIEW
In the stem cell therapy for cancer treatment, along with radiation therapy, very high doses of chemo are applied for the destruction of the cancer cells. The stem cells are also killed in the bone marrow. After its dest...
FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF TRAMADOL HYDROCHLORIDE USING NOVEL CO-PROCESSED SUPERDISINTEGRANTS
In the present work, orodispersible tablets of Tramadol hydrochloride were prepared using novel co-processed superdisintegrants consisting of crospovidone and sodium starch glycolate in the different ratios (1:1, 1:2 &am...
ISOLATION OF Α-GLUCOSIDASE INHIBITORY ACTIVE COMPOUNDS FROM ETHANOL EXTRACT OF KAYU TUAH (ANTIDESMA CELEBICUM MIQ.) LEAVES
Antidesma celebicum Miq. belongs to Euphorbiaceae family has been used as antidiabetic traditional medicine. The aim of the research was to isolate the α-Glucosidase inhibitory compound from ethanol extract of Antidesma...
ISOLATION AND HPTLC ESTIMATION OF AESCULIN FROM OXYSTELMA ESCULENTUM
Oxystelma esculentum R. Br. (Family: Asclepiadaceae) is a perennial twiner growing in water-logged areas of the Indian sub-continent. It is used traditionally as diuretic, laxative and anti-ulcer. The present work deals...
EVALUATION OF ANTIMICROBIAL ACTIVITY AND PRELIMINARY PHYTO-CHEMICAL STUDIES ON WHOLE PLANT OF STACHYTARPHETA JAMAICENSIS (L.)VAHL
The antimicrobial activity and preliminary phyto-chemical studies on whole plant of Stachytarpheta jamaicensis were evaluated. The shade dried and coarsely powdered plant was successively extracted with n-hexane, chloro...