Bombay blood phenotype: Laboratory detection and transfusions recommendations
Journal Title: International Journal of Blood Transfusion and Immunohematology - Year 2016, Vol 6, Issue 1
Abstract
Four main blood types routinely identified today are A, B, AB, and O. Universal donors have type "O" blood, and have no "A" or "B" antigens. In turn, no blood reactions will occur in recipients. Conversely, universal recipients having type "AB" blood will have no antibodies to the "A" or "B" antigens. Bombay phenotype has no "A" or "B" antigens, classifying it as "O" blood type. Furthermore, Bombay phenotype lacks expression of the H antigen, which is present on every blood cell. When mixed with any type of blood other than Bombay blood, hemolytic reactions occur. A 55-year-old male had his blood typed and screened after trauma activation for an eye injury. On forward grouping, the patient was identified as blood type "O". On reverse grouping, agglutination occurred. Laboratory procedures were evaluated and an expanded antigen panel was performed which confirmed this agglutination, which led to the suspicion of a rare blood type. The patient did not require blood transfusion and was further evaluated by New York Blood Center where the diagnosis of Bombay Phenotype was confirmed. This case emphasizes the importance of proper laboratory investigations for rare blood types, preventative strategies, as well as management of Bombay blood type.
Authors and Affiliations
Nicholas Paul Suraci, Maximo Mora
Keywords
Related Articles
- EP ID EP209946
- DOI 10.5348/ijbti-2016-23-CR-3
- Views 112
- Downloads 0
Knowledge, attitude and practice of voluntary blood donation among physicians in a tertiary health facility of a developing country
Aims: The objectives of this study were to assess the knowledge, attitude and practice of voluntary blood donation among physician, to identify and recruit potential voluntary blood donors amongst them and to determine t...
Induced pluripotent stem cells: An update
Introduction: The discovery that the mature cells can be reprogrammed to become pluripotent increased the enormous interest in induced pluripotent stem cell (iPSC) technology for their potential application in biomedical...
Hepcidin testing; establishing reference values for the Namibian blood donor population
Aims: Anemia is a global health concern affecting billions of people worldwide. The diagnostic approach to iron deficiency anemia could be streamlined in an attempt to increase diagnostic sensitivity and to reduce uncert...
Preparation of red cell concentrates in low-income countries: Efficacy of whole blood settling method by simple gravity in Burkina Faso
Aim: This study aims to describe the characteristics of the red cell concentrates (RCCs) produced by whole blood settling in Burkina Faso. Methods: We conducted a cross-sectional study in the blood centers of Ouagadougo...
A guide to organizing a voluntary blood donation camp
Introduction: Human blood is an essential element of human life with no substitute. Voluntary blood donors are the cornerstone of a safe and adequate supply of blood and blood products. The safest blood donors are volunt...