Bombay blood phenotype: Laboratory detection and transfusions recommendations
Journal Title: International Journal of Blood Transfusion and Immunohematology - Year 2016, Vol 6, Issue 1
Abstract
Four main blood types routinely identified today are A, B, AB, and O. Universal donors have type "O" blood, and have no "A" or "B" antigens. In turn, no blood reactions will occur in recipients. Conversely, universal recipients having type "AB" blood will have no antibodies to the "A" or "B" antigens. Bombay phenotype has no "A" or "B" antigens, classifying it as "O" blood type. Furthermore, Bombay phenotype lacks expression of the H antigen, which is present on every blood cell. When mixed with any type of blood other than Bombay blood, hemolytic reactions occur. A 55-year-old male had his blood typed and screened after trauma activation for an eye injury. On forward grouping, the patient was identified as blood type "O". On reverse grouping, agglutination occurred. Laboratory procedures were evaluated and an expanded antigen panel was performed which confirmed this agglutination, which led to the suspicion of a rare blood type. The patient did not require blood transfusion and was further evaluated by New York Blood Center where the diagnosis of Bombay Phenotype was confirmed. This case emphasizes the importance of proper laboratory investigations for rare blood types, preventative strategies, as well as management of Bombay blood type.
Authors and Affiliations
Nicholas Paul Suraci, Maximo Mora
Keywords
Related Articles
- EP ID EP209946
- DOI 10.5348/ijbti-2016-23-CR-3
- Views 113
- Downloads 0
Evaluation of fresh frozen plasma usage at a medical college hospital - A two year study
Aims: The aim of this is study was to evaluate the usage of fresh frozen plasma (FFP) according to indications and to reduce inappropriate usage. Methods: A two year retrospective study was conducted in Medical College...
Analysis of the evolution of the residual risk of HIV transmission at the National Blood Transfusion Center (CNTS) of Lomé (Togo) from January 2008 to December 2012
Aims: This study aimed to: - Analyze the HIV residual risk of transfusion at the CNTS of Lomé from January 2008 to December 2012 - Indicate future directions to strengthen blood safety. Methods: The residual risk of HIV...
Serosurvey of human T cell lymphotropic virus I/II among blood donors in Gombe (Nigeria)
Aim: This study was carried out to determine the prevalence of human T cell lymphotropic virus I/II (HTLV I/II) among blood donors at the Federal Teaching Hospital Gombe (FTHG), North-eastern, Nigeria. Methods: A total...
Induced pluripotent stem cells: An update
Introduction: The discovery that the mature cells can be reprogrammed to become pluripotent increased the enormous interest in induced pluripotent stem cell (iPSC) technology for their potential application in biomedical...
Knowledge, attitude and practice of voluntary blood donation among physicians in a tertiary health facility of a developing country
Aims: The objectives of this study were to assess the knowledge, attitude and practice of voluntary blood donation among physician, to identify and recruit potential voluntary blood donors amongst them and to determine t...