COMPARISION OF POTENCY OF ANTI BACTERIAL ACTIVITY AND ANTI INFLAMMATORY ACTIVITY OF 10 YEARS AND 100 YEARS OLD BARK EXTRACTS OF AZADIRACHTA INDICA
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 4
Abstract
Azadirachta indica (Meliaceae) commonly known as neem contains many biologically active compounds including alkaloids, flavonoids, triterpenoids, phenolic compounds, Carotenoids, steroids and ketones, azadirachtin. Oil from the leaves, seeds and bark possesses a wide spectrum of antibacterial action against Gram-negative and Gram-positive microorganisms, including M. tuberculosis and streptomycin resistant strains. The present study was undertaken to evaluate the comparision of potency of anti bacterial and anti-inflammatory activities of 10 and 100 years old bark extract of Azadirachta indica. The antibacterial activity was performed by using both gram positive and gram negative organisms viz., Bacillus Subtilis, E. coli and Staphylococcus Aureus. The anti-inflammatory activity was evaluated by using carrageenan induced paw edema method in rats. From the results of anti bacterial activity and anti-inflammatory activity, it has been concluded that 100 years old neem bark extract showed greater activities than the 10 years old neem bark extract.
Authors and Affiliations
Vijaya Kumar G, Srinivas N, P Sravanthi, Sravani B
Keywords
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