A comprehensive review on superdisintegrants used in orodispersible tablets
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2014, Vol 2, Issue 4
Abstract
Orodispersible Tablets disintegrate and/or dissolve rapidly in the saliva without the need for water. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fastdissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate. When put on tongue, this tablet disintegrates instantaneously, releasing the drug, which dissolves or disperses in the saliva. Some drugs are absorbed from the mouth, pharynx and oesophagus as the saliva passes down into the stomach. In such cases, bioavailability of drug is significantly greater than those observed from conventional tablet dosage form. Their growing importance was underlined recently when European Pharmacopoeia adopted the term “Orodispersible Tablet” as a tablet that to be placed in oral cavity where it disperses rapidly before swallowing.
Authors and Affiliations
Digpati Roy, Debjit Bhowmik, K. P. Sampath Kumar
Keywords
Related Articles
- EP ID EP33232
- DOI -
- Views 271
- Downloads 0
Application of Nanotechnology in Commercial field
The materials which are processing to a grain size of a billionth of a meter are called nanomaterials or nanoparticles. The naturally occurring or the incidental byproducts of combustion processes are usually physicall...
INVITRO ANTI-INFLAMMATORY ACTIVITY OF STRYCHNOS POTATORUM LINN SEED BY HRBC MEMBRANE STABILIZATION
In the present study, strychnos potatorum linn belonging to the family Loganiaceae (Strychnaceae) was studied. It is a folkloric medicinal plant used to treat antibacterial, antifungal, anti diabetic, antioxidant and a...
Comparative In- vitro evaluation of commercially available sustained release Aceclofenac tablets
Purpose: The objective of the study was to determine the difference between commercial available Aceclofenac sustained release tablets. Methods: Four commercially available tablets Hifenac SR(A), Acceclowoc SR(B), Acel...
PLANTS USED IN HEPATOPROTECTIVE REMEDIES IN TRADITIONAL INDIAN MEDICINE
There is no plant in this Universe which is non-medicinal and which cannot be made of use for many purposes and by many modes. This definition rightly suggests that in principle all plants have a potential medicinal va...
Synthesis, formulation and evaluation of Chalcone as potent antimicrobial agent
In a wide search program towards new and efficient antimicrobial agent chalcone has been synthesized by condensing benzaldehyde derivatives with acetophenone derivatives in dilute ethanolic sodium hydroxide solution at...