Diagnostic Accuracy of Mammography and Ultrasonography in Assessment of Breast Cancer
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Diagnostic efforts for breast cancer are critical because the disease has a high rate of successful outcomes with early identification and treatment. The mammography (MG) and ultrasonography (USG) are individually effective diagnostic modalities for palpable abnormalities of the breast. This prospective hospital based study was carried out with aim to evaluate breast lesions using mammography and ultrasonography individually and in combination with fine needle aspiration cytology (FNAC) correlation. Material and Methods: Study participants were all women with palpable and non palpable breast lesions detected on clinical examination/self breast. Total 53 patients were studied, based on inclusion/ exclusion criteria. Study tools were mammography machine (Digital Mammography Novation DR. SIEMENS) and USG machine (WIPRO G E Health care Ultrasound LOGIC –P5). Mammography was performed in a stand type Siemens Novation which is a radiographic stand to radiograph the subject in a standing or sitting position in combination with mammographic x-ray tube assembly with compression paddle. Results: The sensitivity, specificity, Positive predictive value (PPV) and Negative Predictive value (NPV) of mammography in detecting carcinoma breast were 77.8%, 97.7%, 87.5% and 95.6% respectively. The sensitivity, specificity, PPV and NPV of USG in detecting carcinoma breast were 55.6%, 97.7%, 83.3% and 91.5% respectively. In our study population 83.0% breast lesion were benign and out of them 77.27% were diagnosed by mammography alone and 72.7% were diagnosed by USG alone. When these modalities were combined, 97.7% of the lesions were diagnosed. The correlation coefficients of mammography alone (0.79), USG alone (0.63) and mammography and USG combination (0.88) with FNAC are all positive, and P values are significant of all the modalities. Conclusion: This study confirms that the mammography and ultrasonography when combined have significantly higher sensitivity and negative predictive value than observed for a single modality in detecting the palpable abnormalities of the breast.
Authors and Affiliations
P K tiwari, Suvendu Ghosh, V K Agarwal
Keywords
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