FORMULATION AND EVALUATION OF FLOATING DRUG DELIVERY SYSTEM OF CLARITHROMYCIN TABLETS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 4
Abstract
The present study focused on the development of gastroretentive technology which will deliver the antibiotic at predetermined rate to achieve the local concentration enough to act as antibacterial against H.Pylori. This technology ensures the maximum utilization of the drug with minimum side effects and maximum patient compliance and also with reduced antibiotic resistance by the bacterium. The tablet contain 15% and 20% having Floating lag time (FLT) 63 seconds and 64 seconds and the drug release was found to be 62.73% and 53.72 respectively. Increasing the polymer ratio the FLT was increase but the drug release was decreased.
Authors and Affiliations
Priyanka Shukla, Ajay Yadav
Keywords
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