Formulation and in-vitro evaluation of Divalproex sodium sustained release matrix tablets
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 1
Abstract
Divalproex sodium 250 mg sustained release tablets were developed by using polymers like PVPK 30, HPMC K4M, HPMC K100M, Ethyl cellulose 45 CPS and Ethyl cellulose 20 CPS. Nine formulations were prepared with varying concentration of polymers. In-vitro dissolution studies were conducted for 12 hours. Formulation F9 showed better results in drug release pattern compared to other formulations.
Authors and Affiliations
A. Chitra Latha, D. Jeevan Mani Babu, B. Nagendra Babu
Keywords
Related Articles
- EP ID EP33430
- DOI -
- Views 308
- Downloads 0
Evaluation of hypo lipidemic and antioxident properties of methanolic extract of leaves of Tectona grandis linn on Mithionine induced model in Wister albino rats
The Methanolic extract of Tectona grandis leaves was subjected to phytochemical screening to find the chemical constituents present. The extract revealed the presence of carbohydrates, alkaloids, phytosterols, proteins...
COMPARISION OF POTENCY OF ANTI BACTERIAL ACTIVITY AND ANTI INFLAMMATORY ACTIVITY OF 10 YEARS AND 100 YEARS OLD BARK EXTRACTS OF AZADIRACHTA INDICA
Azadirachta indica (Meliaceae) commonly known as neem contains many biologically active compounds including alkaloids, flavonoids, triterpenoids, phenolic compounds, Carotenoids, steroids and ketones, azadirachtin. Oil...
Effect of ethanol/water extract of Crinum jagus on glycemia, lipids parameters and body weight gain on high-sugar diet fed rats
Crinum jagus is used in Cameroon western region folk medicine in the management of diabetes and obesity. The effects of ethanol/water extract of C. jagus were evaluated on two month old Wistar rats submitted to a high...
Prevalence & comparison of Cigarette smoking habits among health care professional students
Smoking cigarette is by far the most important risk factor for oral cancer and pre cancer & its use is a medical addictive condition. Several meta-analyses of the impact of smoke free legislation have been published ov...
Formulation and evaluation of gastro retentive nifedipine floating tablets
The objective of present investigation is to develop and evaluate Gastro retentive floating tablets of Nifedipine to achieve controlled drug release with reduced frequency of drug administration, reduced side effects a...