Incidence, clinico- microbiological profile in adult patients with lower respiratory tract infections in a tertiary care hospital
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 10, Issue 1
Abstract
Background: Lower respiratory tract infection (LRTI) is one of the commonest encountered disease in the hospital with wide range of disease manifestations like pneumonia, bronchiectasis, acute bronchitis, and acute exacerbation of lung disease. The timely diagnosis and appropriate antibiotic therapy can reduce the morbidity and mortality in a patient. Objectives: This study aims to isolate the pathogens causing LRTI and to study its antibiogram pattern with special reference to ESBL, MBL and Amp C detection which helps in prompt start of antibiotics. Materials and methodology: A total of 55 sputum samples were collected from both inpatient and outpatient departments from August 2018 to September 2018.Out of 55 samples, only 16 samples were poceeded for sputum culture according to Barlett grading’s of sputum sample. Sputum samples were inoculated in blood agar, chocolate agar and Mac conkey agar and further biochemical tests were performed according to the standard protocol.Antibiotic Susceptibility tests was performed along with detection of ESBL, MBL, AmpC and Mehicillin resistance as per standard protocols. Result: Out of 16 samples, Pseudomonas aeruginosa and Klebsiella pneumoniae was isolated in 10 sputum samples accounting for 5 each, 2 were Acinetobacter species followed by 4 isolates each of Citrobacter spp, Escherichia.coli, Streptococcus pneumoniae and Staphylococcus aureus. 40% of the Klebsiella pneumoniae isolates produced ESBL and 20% produced AmpC. The one isolate of Citrobacter spp produced both ESBL and AmpC. 60% of the Pseudomonas aeruginosa and 50% of the Acinetobacter spp produced MBL.
Authors and Affiliations
Annet Olinda Dsouza, Rajeswarie S
Keywords
Related Articles
- EP ID EP590563
- DOI 10.26611/10081012
- Views 72
- Downloads 0
Prevalence of extended β lactamases, Amp C and metallo beta lactamases among gram negative clinical isolates at a tertiary care centre in South India
Background: Resistance of Gram negative bacteria to broad spectrum antibiotics is posing a clinical threat during the last decade. These ESBL and MBL producing organisms have a potential for rapid dissemination and hence...
Effect of extracts of lichens of different solvent races against clinically infectious bacteria
Background: Lichens are well-known prolific sources of biologically active natural products. They are symbiotic organisms of fungi and algae that synthesize numerous metabolites called the “lichen substances”, which comp...
Comparison of immunochromatogenic method of antigen detection and Giemsa staining with polymerase chain reaction (PCR) for detection of chlamydia trachomatis infection in infertile women
Context: Chlamydial infection is a silent epidemic. The varied prevalence of chlamydial infection in India, leads to an urgent need to look for simple, inexpensive and sensitive tests for early diagnosis. Aims: To determ...
Burden of hepatitis B virus infection at tertiary care hospital
Background: Hepatitis B is a life threatening disease, endemic throughout the world especially in tropical and developing countries like India. Prevalence of this infection varies in different geographical areas. Estimat...
Comparative study of enzyme linked immunosorbent assay and immunochromatography for rotavirus detection in children below five years with acute diarrhoea
Background: Early diagnosis of rotavirus infection prevents unnecessary use of antibiotics, minimizes it’s spread and helps to determine the appropriate treatment. Rapid test using latex agglutination or lateral flow imm...