Incidence, clinico- microbiological profile in adult patients with lower respiratory tract infections in a tertiary care hospital
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 10, Issue 1
Abstract
Background: Lower respiratory tract infection (LRTI) is one of the commonest encountered disease in the hospital with wide range of disease manifestations like pneumonia, bronchiectasis, acute bronchitis, and acute exacerbation of lung disease. The timely diagnosis and appropriate antibiotic therapy can reduce the morbidity and mortality in a patient. Objectives: This study aims to isolate the pathogens causing LRTI and to study its antibiogram pattern with special reference to ESBL, MBL and Amp C detection which helps in prompt start of antibiotics. Materials and methodology: A total of 55 sputum samples were collected from both inpatient and outpatient departments from August 2018 to September 2018.Out of 55 samples, only 16 samples were poceeded for sputum culture according to Barlett grading’s of sputum sample. Sputum samples were inoculated in blood agar, chocolate agar and Mac conkey agar and further biochemical tests were performed according to the standard protocol.Antibiotic Susceptibility tests was performed along with detection of ESBL, MBL, AmpC and Mehicillin resistance as per standard protocols. Result: Out of 16 samples, Pseudomonas aeruginosa and Klebsiella pneumoniae was isolated in 10 sputum samples accounting for 5 each, 2 were Acinetobacter species followed by 4 isolates each of Citrobacter spp, Escherichia.coli, Streptococcus pneumoniae and Staphylococcus aureus. 40% of the Klebsiella pneumoniae isolates produced ESBL and 20% produced AmpC. The one isolate of Citrobacter spp produced both ESBL and AmpC. 60% of the Pseudomonas aeruginosa and 50% of the Acinetobacter spp produced MBL.
Authors and Affiliations
Annet Olinda Dsouza, Rajeswarie S
Keywords
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- EP ID EP590563
- DOI 10.26611/10081012
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