Preclinical evaluation of antispermatogenic activity of Curcuma amada on cell phone radiation induced infertility in rats
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2015, Vol 3, Issue 6
Abstract
To study the ability of the electromagnetic signals emitted by cellular mobile telephony to affect the biological function of living organisms and mobile radiation exposures are changes in the structure and functional behavior, and disturbances of multiple hormone systems that impact male reproduction. The changes in spermatozoa result from oxidative damage, calcium deficiency and disturbed signal transduction. Since the mobile radiation causes toxicity in several ways and need to be developed with minimal side effects. Herbal drugs were found to be more beneficial than synthetic drugs. The pretreatment of Curcuma amada significantly improved the sperm count, and motility, also declined in cell phone radiation induced infertility in rats. The extract has shown significant influence on the level of Testosterone hormone indicating its protective effect against radiation induced infertility.
Authors and Affiliations
Devarinti Revana Siddappa, Ravi babu, Varaprasad, Shaik Jilani, Shaik Rabbani basha, Veena. V, Gowtham Kumar
Antimycobacterial and antimicrobial studies of newly synthesized 3-(4-(6- methylbenzo[d]thiazol-2-yl) phenyl)quinazolin-4(3H)-ones
7-Chloro-2-(substituted)-3-(4-(6-methylbenzo[d]thiazol-2-yl) phenyl) quinazolin-4(3H)-ones 1- 12 have been prepared from the substituted acids 1(a-l), which were converted to substituted acetyl chlorides 2(a-l) and cyc...
Simultaneous estimation of Diethylcarbamazine Citrate and Cetirizine Hydrochloride in formulation by RP-HPLC
A simple reverse phase liquid chromatography method has been developed and validated for simultaneous determination of Diethylcarbamazine citrate and Cetirizine Hydrochloride is carried out by using a mobile phase cons...
DIABETES EPIDEMIC IN INDIA: RISK FACTORS, SYMPTOMS AND TREATMENT
Diabetes is a metabolism disorder in which the pancreas in the human body fails to produce insulin, or is unable to use the insulin produced in an effective manner. Most of the food we eat is broken into glucose, which...
A Review on various HPLC and Spectrophotometric methods for determination of Rosuvastatin Calcium and Fenofibrate in combined dosage forms
Rosuvastatin belongs to the category of statins, used in combination with calcium channel blockers, analgesics and other class of cardiovascular disease drugs in the treatment of high cholesterol and related conditions...
Synthesis of novel Tetrazole derivatives and their biological evaluation
Tetrazole have very important biological activity. We have synthesized the 10 novel tetrazole derivatives characterized by 1H NMR 13C NMR HRMS and evaluated antibacterial and antifungal activity. Among the compounds co...