Study of effect of solubility of a sparingly water soluble drug in presence of surfactant
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2016, Vol 5, Issue 5
Abstract
Solubility plays an important role in dissolution and absorption of drug. Benzoic acid has less solubility in aqueous media. The aim of present study was to study the effect of solubility enhancing agents at room temperature on the solubility of benzoic acid. Sodium Lauryl Sulphate (SLS) in various concentrations were used to study the solubility of Benzoic acid in water. The solubility of benzoic acid in water is directly proportional to the concentration of the surfactant added. The solubility of benzoic acid increases with increase in concentration of surfactant.
Authors and Affiliations
Ashish Kumar Gupta*| Department of pharmacy, V.B.S.Purvanchal University, Jaunpur, Amita Tilak| Department of pharmacy, G.S.V.M. Medical College, Kanpur, Sudhir Singh Gangwar| Department of pharmacy, G.S.V.M. Medical College, Kanpur, Minakshi Verma| Department of pharmacy, G.S.V.M. Medical College, Kanpur
Keywords
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