Study of platelet count, PT and aPTT in preelclampsia patients at tertiary care centre
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 5, Issue 3
Abstract
Background: Hypertensive disorders complicate 5%-10% of all pregnancies and together they form one member of the deadly triad, along with haemorrhage and infection that contribute greatly to the maternal morbidity and mortality rates. Pre-eclampsia complicates 2-8% of pregnancies. There is a distinct possibility of accentuation of the hypercoagulable state of pregnancy during pre-eclampsia. The aim of our study are the changes in platelet count, Prothrombin time and Activated partial thromboplastin time in preeclampsia patients in their third trimester. So this parameters will guide us for the management before the patient goes into complications. Methods: A comparative study from December 2015 to October 2017. Total 167 pregnant women in their third trimester. Out of 167, 100 healthy pregnant women as a control and 67 patients with pre eclampsia. Blood was drawn from the study subjects in Obstetrics ward and transported to the laboratory immediately for Platelet count, Prothrombin time (PT) and Activated partial thromboplastin time (aPTT). Results: It was observed that in preeclampsia, 10 (14.93%) patients had Platelet Count in the range 0.6-1.6, 50 (74.62%) had between 1.6-2.6 and 07(10.45%) had between 2.6-3.6. Prothrombin time in 23 (34.33%) patients had in the range of 12-14, 25 (37.31%) had between 14-16, 15 (22.39%) had between 16-18, 03(4.48 %) had between 18 -20, 01 (1.49%) had in between 20-22. Activated partial thromboplastin time in 10 (14.92%) pateints had in the range 25-30, 16 (23.88%) had between 30-35, 18 (26.87%) had between 35-40 and 19 (28.36%) had between 40-45 and 4 (5.97%) had between 45- 50. Conclusion: Raised aPTT and low platelet count are associated with the severity of the disease. However PT does not show a significant change in the present study. Simple and routine tests like platelet count and aPTT, are helpful in suspecting the derangement in the coagulation status early in the course of the disease and plan preemptive management strategies. So we can reduce systemic complications and maternal death due to Pregnancy Induced Hypertension
Authors and Affiliations
Khushbu B Patel, Bharat V Bhetariya, Nandini J Desai
Keywords
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