Synthesis and Antibacterial Activity of 4-Methoxy Phenyl Propenone Chalcones
Journal Title: Scholars Academic Journal of Pharmacy - Year 2018, Vol 7, Issue 6
Abstract
Abstract: Chalcones belongs to a class of naturally occurring compounds called flavonoids which are found in plants and they are known to possess variety of biological activities. They are very useful and good lead compounds in drug research and are continuously been tested for activity against various infectious diseases. Series of 4-methoxy phenyl propenone chalcone moieties were synthesized by modified Aldol condensation reaction involving aromatic aldehydes and acetophenones at low temperature and the progress monitored by TLC. The various 4-methoxy phenyl propenones did not show any antibacterial activity, therefore may substantiate that most chalcones are made active by the enzyme chalcone synthetase.
Authors and Affiliations
D. Ere, E. Dode, C. O. Usifoh
Keywords
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