THE ROLE OF HEAVY IONS IN FAST NEUTRON THERAPY
Journal Title: World Science - Year 2018, Vol 1, Issue 2
Abstract
The use of fast neutrons has a number of features which differ very much from gamma-therapy. They were checked experimentally and in clinic, and sometimes the outcome after neutron irradiation was unpredictable. Early and late reactions from side of tumor and normal tissue were sudden. The sequence of processes occurring during the movement of neutrons through the organic tissue is not completely understood and poorly studied. And the main question - what causes such a strong destruction of cells after fast neutrons irradiation. The aim of this work was to understand role of heavy ions in fast neutron irradiation, as well as to set correct task for further research. The analysis of data obtained on cyclotron U-120 was carried out. It was shown that heavy ions and not recoil protons make main contribution to radiobiological effect in irradiating of organic tissue with neutrons. Nitrogen nucleus takes a special place in the process of destruction of cells. The levels of excitation of 14N start about 2.3 MeV and the density of excitation levels is much higher than that for other elements, for example, 16О or 12C. When 14N absorbs a neutron, it is converted to 15N with excitation energy of about 15 MeV, which leaves behind the ruined pieces of cells while moving. Recoil protons are absorbed in the very place of origin. Therefore, heavy ions play a major role in the destruction of cells after fast neutron irradiationIt seems that the effect of irradiation depends on many variables and is not uniquely determined by absorbed dose (as integral value).
Authors and Affiliations
Oksana Kozak, Anatolij Shvedov, Olexandr Trembach
Keywords
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