Asian Pacific Journal of Health Sciences

Asian Pacific Journal of Health Sciences

Basic info

  • Publisher: IJPMR Publishing Press, India.
  • Country of publisher: india
  • Date added to EuroPub: 2019/Sep/29

Subject and more

  • LCC Subject Category: Medicine, Health and Wellness
  • Publisher's keywords: Medicine, Health
  • Language of fulltext: english
  • Time from submission to publication: 6 weeks

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Open access & licensing

  • Type of License: CC BY
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 2014
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: Other
  • Deposit policy registered in: None

This journal has '459' articles

Correlation of body mass index, degree of airflow obstruction, dyspnea scale, and exercise index with pulmonary hypertension

Correlation of body mass index, degree of airflow obstruction, dyspnea scale, and exercise index with pulmonary hypertension

Authors: Namrata G Modi
Year: 2018, Volume: 5, Number: 1
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Abstract

Introduction: Cardiovascular disease is major comorbidity and most frequent disease coexisting with chronic obstructive and pulmonary disease (COPD). BODE (body mass index, degree of airflow obstruction, dyspnea scale and exercise) index is a multi-dimensional tool to assess severity of COPD. This study was undertaken to assess the BODE index as a predictor of development of pulmonary hypertension (PHT) in COPD patients. Aims: The aim of the study was to assess the corelation between the BODE index and PHT as diagnosed by 2DEcho. Materials and Methods: We conducted a prospective study over a period of 2 years on 60 stable COPD patients by evaluating the BODE index and categorizing into mild, moderate, and severe COPD cases on the basis of spirometry and into 4 quartiles on the basis of BODE index value (scores 0–2, 3–4, 5–6, and 7–10 ). PHT was defined in this study as pulmonary artery systolic pressure ≥30 mmHg. We investigated the prognostic value of BODE quartiles for prediction of development of PHT in COPD patients. Results: In our study, spirometry showed mild obstruction in 16.7%, moderate obstruction in 26.7%, severe obstruction in 38.3%, and very severe obstruction in 18.3% of patients. According to BODE score, 52% of patients were quartile 1, 21% quartile 2, 15% quartile 3, and 12% were quartile 4. In this study group, 46.7%, 31.7%, 11.7%, and 10.0% patients were with no, mild, moderate, and severe PHT, respectively. Conclusion: COPD patients with higher BODE index should also be looked for other causes of developing PHT, and such patients should undergo 2DEcho on regular intervals.

Keywords: Body mass index; degree of airflow obstruction; dyspnea scale and exercise index, chronic obstructive and pulmonary disease, pulmonary hypertension, spirometry
Prevalence and correlates of cognitive adverse outcomes among epileptic patients - Evidence from a cross-sectional study

Prevalence and correlates of cognitive adverse outcomes among epileptic patients - Evidence from a cross-sectional study

Authors: Subodh Pandey
Year: 2018, Volume: 5, Number: 1
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Abstract

Background: Epilepsy accounts for 1% of the global burden of disease and affects over 60 million people worldwide imposing a large economic burden on global health-care systems. The objective of the present study was to determine the prevalence of cognitive dysfunctions among epileptic patients. Material and Methods: It was a cross-sectional study, and 148 patients diagnosed with epilepsy were screened using mini-mental state examination (MMSE). Results: There were 148 epileptic patients involved in this study. The lowest MMSE score was 16, whereas the mean and median were 26.92 and 28, respectively. Females had higher mean MMSE scores than males (26.57 vs. 27.31). The marital status (divorced/widow/separated), younger age of diagnosis (<10 years), elderly (>60 years), longer duration (>10 years), and higher seizure frequency were associated with lower MMES score. Conclusion: The low MMSE score was associated with poor prognosis indicators of epilepsy.

Keywords: Cognitive adverse effects, epilepsy, India, mini-mental state examination
A study of aerobic bacterial culture and antibiotic susceptibility pattern of diabetic foot ulcer

A study of aerobic bacterial culture and antibiotic susceptibility pattern of diabetic foot ulcer

Authors: Shital Sangani
Year: 2018, Volume: 5, Number: 1
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Abstract

Background: Diabetes mellitus is a chronic disorder that affects large segments of the population in the whole world. Aim: The aim of the study was to isolate and identify aerobic bacteria from diabetic foot ulcers (DFU) and to determine their antibiotic susceptibility pattern. The reason for the increased incidence of DFU involves the interaction of several pathogenic factors such as neuropathy, abnormal foot ulcer, and peripheral arterial diseases. Materials and Methods: A prospective study was conducted for a period of 6 months in Sir Sayajirao General Hospital and Medical College, Vadodara, Gujarat. 175 DFU patients attending the surgery ward were included in the study. Two swabs were taken from each patient and processed by standard techniques to isolate and identify various bacterial species. Antibiotic susceptibility testing was done by Kirby-Bauer’s disc diffusion method for all the aerobic bacterial isolates. Results: It was observed from the result that common pathogens isolated from the DFU were Klebsiella species and acinetobacter followed by Pseudomonas and Proteus species, as well as Escherichia coli. Pseudomonas species, isolates were highly resistant to most tested antibiotics except piperacillin-tazobactam, levofloxacin, and meropenem. Cefoperazone-sulbactam and levofloxacin are more active against E. coli followed by gentamycin. Ofloxacin is more active against Staphylococcus aureus followed by gentamycin and cefoxitin. Cefoperazone-sulbactam is active against Proteus mirabilis followed by piperacillin-tazobactam. Conclusion: This study concludes that DFU infection is mostly polymicrobial in nature and appropriate antibiotic therapy is required for treatment of DFU.

Keywords: Aerobic bacteria, antibiotic, diabetes, diabetic foot ulcer, monomicrobial, polymicrobial
Clinicocytopathological study of breast lump in the non-malignant categories

Clinicocytopathological study of breast lump in the non-malignant categories

Authors: Sunil Vitthalrao Jagtap
Year: 2018, Volume: 5, Number: 1
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Abstract

Background: Benign breast lesions are common clinical presentation in women. The early detection and diagnosis play an important role in the treatment of various breast lesions. Aims and Objectives: The aim is to study various cytological changes in non-malignant breast lesions and its clinical correlation. Materials and Methods: This is prospective, observational, analytical study in a consecutive 50 cases of breast lump at tertiary care hospital. Results: A total of 50 breast lumps were studied for fine-needle aspiration cytology (FNAC). Among which, 48 patients were female and 2 were male. The age range was from 15 to 62 years. The common age group affected was in 21–30 years of age. The most common clinical presentation was breast lump followed by pain in the breast. The left side breast was more affected (56%) than the right side. Among non-malignant breast lesions, fibroadenoma (48%) was common diagnosis, followed by mastitis (28%), fibrocystic change (10%), papilloma (4%), gynecomastia (4%), lipoma (2%), simple cyst (2%), and benign phyllodes (2%). The cytological diagnosiswas correlated with histopathology which showed accuracy in 91.66%. Conclusion: In our study, benign breast lesion of fibroadenoma was the most common benign breast lesion and the younger age group 21–30 years was found most commonly affected. FNAC is also very useful in diagnosing inflammatory lesions so that they can be treated as early as possible.

Keywords: Benign breast lesions, breast lump, cytopathology breast
An alarming presence of methicillin-resistant Staphylococcus aureus in a major hospital in the Henan province, China: A five-year observation

An alarming presence of methicillin-resistant Staphylococcus aureus in a major hospital in the Henan province, China: A five-year observation

Authors: Adi Idris
Year: 2018, Volume: 5, Number: 1
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Abstract

Background: Health care-associated infection is a major cause of morbidity and mortality. Methicillin resistant Staphylococcus aureus (MRSA) is one of the main causes of bloodstream infections, pneumonia and surgical site infections in hospitals. Methodology: Bodily fluids and skin swab samples from in-patients from a major hospital in Henan province were collected between 2013 and 2017. Samples were then cultured, identified and subjected to drug susceptibility testing on a BD Phoenix™ 100. Results: A 5-year observation of the presence of MRSA in this hospital revealed a high incidence of MRSA, compared to other staphylococci species isolated from in-hospital patients in 2013 (74.4%). Implementation of hygiene measures and the introduced usage of vancomycin in therapy curbed the number of isolated MRSA to 44.4% in 2017. Conclusion: Early identification of MRSA is essential for further therapeutic treatment and the control of rapid expansion of

Keywords: Antibiotic resistance, henan, hospital, methicillin-resistant Staphylococcus aureus, staphylococci
Microbiological study of methicillin-resistant Staphylococcus aureus isolated from wound samples at a tertiary care hospital, Central India

Microbiological study of methicillin-resistant Staphylococcus aureus isolated from wound samples at a tertiary care hospital, Central India

Authors: Prashant Peshattiwar
Year: 2018, Volume: 5, Number: 1
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Abstract

Background: Staphylococcus aureus continues to be a dangerous pathogen for both community-acquired as well as hospital-associated infections. S. aureus resistant to methicillin were reported soon after its introduction in October 1960. Methicillin-resistant S. aureus (MRSA) is now endemic in India. MRSA has recently emerged as a major nosocomial pathogen worldwide with a significant morbidity and mortality. Materials and Methods: This study was thus undertaken to characterize MRSA isolates, isolated from wound samples from a tertiary care teaching hospital in Central India and to also probe antibiotic susceptibility of its clinical isolates. Results: About 120 MRSA isolates from various clinical samples such as pus swabs and aspirates, blood, urine, sputum, and endotracheal tube aspirates were collected and processed in the laboratory for various tests. Of 120 isolates subjected to gelatin liquefaction test with appropriate controls, 104 were found to be positive while 16 were tested negative. Majority of the hospital-associated MRSA (HA-MRSA) patients were in the age group of >50 years of age 42 (35%) followed by the 41–50 years of age group 26 (21.7%). The age in the HA-MRSA group varied from 18 to 75 years with mean age of 41.2 ± 22.29. Majority of the HA-MRSA infections presented as cellulitis (41.9%), followed by abscess (28.9%) and post-operative wound discharge (23.8%), whereas most of the community-associated-MRSA infections presented as abscesses (83.5%), followed by furuncle (9.6%), and cellulitis and carbuncle (2.8% each). Among 120 isolates subjected to alkaline phosphatase test, 114 were found to be phosphatase positive while 6 being phosphatase negative. Conclusion: Our study is a preamble to enable epidemiologists to understand the nature of MRSA isolates in this part of India. There is a need to study epidemiology of such infections. Robust antimicrobial stewardship and strengthened infection control measures are required to prevent spread and reduce emergence of resistance.

Keywords: Biochemical test, methicillin-resistant Staphylococcus aureus, microbiological study, prevalence, Staphylococcus, wounds
A rare case of pleomorphic adenoma of the tongue

A rare case of pleomorphic adenoma of the tongue

Authors: T.R Sruthi
Year: 2018, Volume: 5, Number: 1
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Abstract

Pleomorphic adenoma of minor salivary glands accounts for less than 3% of all head and neck tumors. It is a benign tumor. Palate is the most common site followed by upper lips. Tongue is an unusual site, and there are only 29 reported cases in literature as per our knowledge. We present a case of a 38-year-old female patient who presented with mass in the anterior tongue that was diagnosed as pleomorphic adenoma and was treated by surgical excision.

Keywords: Benign tumor, minor salivary gland, oral cavity, palate, tongue
Local mesh patterns for medical image segmentation

Local mesh patterns for medical image segmentation

Authors: Nookala Venu
Year: 2018, Volume: 5, Number: 1
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Abstract

In this paper, local mesh patterns (LMeP) feature extractor is proposed for medical image segmentation. The local region of image is represented by LMeP, which are evaluated by taking into consideration the magnitude of the local difference between the center pixel and its neighbors. First, image split into subblocks and LMeP features are extracted from each subblock. Once the image has been split into blocks of roughly homogeneous texture, we apply an agglomerative procedure to merge similar adjacent regions until one of the two stopping criteria is satis1ed. At each stage, we merge the pair of adjacent regions which have the largest merger importance (MI) value. Based on MI the regions are merged and then form the segmented regions for medical image segmentation application. Experimental results are tested on benchmark magnetic resonance image database for medical image segmentation application. Results after being investigated, proposed method shows a significant improvement for segmentation of images.

Keywords:
Carotid intima-media thickness as a predictor of atherosclerosis in diabetic and non-diabetic subjects - A study from tertiary care hospital in coastal city of South India

Carotid intima-media thickness as a predictor of atherosclerosis in diabetic and non-diabetic subjects - A study from tertiary care hospital in coastal city of South India

Authors: G Vikas Naik
Year: 2018, Volume: 5, Number: 1
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Abstract

Background and Objectives: Atherosclerosis typically occurs over a period of many years, usually many decades. After a generally prolonged “silent” period, atherosclerosis may become clinically manifest. Evaluation of intimal medial thickness is considered as surrogate marker of atherosclerosis. B-mode ultrasound was a suitable non-invasive method to visualize the arterial walls and to monitor the early stages of the atherosclerotic process. Materials and Methods: This is a cross-sectional hospital-based study. A total of 100 patients were selected with 50 patients each in diabetic and non-diabetic groups. After taking consent, patients were subjected for carotid Doppler examination. Results: The mean intimal medial thickness values of the diabetic subjects (0.12) were significantly higher than those of the non-diabetic (0.07 mm) subjects (P < 0.001). Both in the normal and diabetic subjects, these values increased with age. At any given age, the diabetic subjects had higher values than the non-diabetic subjects. Intimal medial thickness showed a positive correlation with age, gender, hypertension (HTN), hemoglobin A1C, and duration of diabetes with statistically significant P value. Conclusion: Diabetic subjects have higher intimal medial thickness values than non-diabetic subjects. Diabetes, duration of diabetes, age, gender, and HTN are the most important risk factors associated with increased intimal medial thickness.

Keywords: Atherosclerosis, carotid intima-media thickness, ultrasound
Determinants of anemia among pregnant women in jeneponto regency

Determinants of anemia among pregnant women in jeneponto regency

Authors: Andi Imam Arundhana
Year: 2018, Volume: 5, Number: 1
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Abstract

Background: The prevalence of anemia among pregnant women is becoming public health problem worldwide including Indonesia. The aim of this study was to examine the prevalence and determinant factors of anemia among pregnant mothers in Jeneponto Regency, Indonesia. Methods: This cross-sectional study was conducted in six sub-districts (Bangkala, Bontoramba, Tamalatea, Binamu, Tarowang, and Kelara subdistricts) in Jeneponto Regency, South Sulawesi, Indonesia. A total 616 samples of pregnant women were evaluated. The DiaspectTM tool was used to measure hemoglobin (Hb) by Cyanmethemoglobin method. Data regarding household characteristics, pregnancy history, maternal age, supplementary feeding (PMT) programme enrolment, and dietary pattern was collected by trained enumerators. Data were analyzed using chi-square and performed by SPSS. Results: There was 17.3% of study participant did not complete primary school or never attended school. As many as 82.4% of households had members that still actively smoked. The majority of households had latrines (62.0%), homes constructed from wood/bamboo (69.5%), and drinking water from cement wells (28.2%). The average body weight and height were 53.88 kg and 152.37 cm, respectively. The average middle-upper arm circumference was 25.72 cm, and mean Hb was 11.31 g/dL. The prevalence of anemia in Jeneponto Regency reached 39.08%. Only two determinant factors were significantly associated with anemia: Gestational age and PMT programme enrollment. Conclusion: The prevalence of anemia in pregnant women in Jeneponto Regency remains very high and exceeds global and national prevalence rates. Gestational age and PMT programme enrollment are two anemia determinant factors among pregnant mothers in Jeneponto Regency.

Keywords: Anemia, pregnant women, determinant factors, gestational age, food supplementation, and nutritional deficiency
A report on the quality control parameters of Cressa cretica Linn., Convolvulaceae

A report on the quality control parameters of Cressa cretica Linn., Convolvulaceae

Authors: Priyanka Bhardwaj
Year: 2018, Volume: 5, Number: 1
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Abstract

Introduction: The present study was aimed at pharmacognostical, phytochemical, and pharmacological evaluation of Cressa cretica Linn., (fruit) family - Convolvulaceae. Materials and Methods: Pharmacognostical investigation was carried out by performing organoleptic, microscopical, and physicochemical evaluation, i.e.,ash values, extractive values, moisture content, swelling index, foaming index, and foreign matter. The obtained results showed that the moisture content was found to be 2.25%. Similarly, swelling index was recorded to be 0.8 cm. Foaming index (<100). Phytochemical investigation included successive Soxhlet extraction, the obtained extractive values were 1.25%, 0.05%, 5.25%, 29%, and 22.80% for petroleum ether, chloroform, ethyl acetate, ethanol, and distilled water, respectively. The preliminary qualitative phytochemical screening revealed the presence of carbohydrates, phenolic compounds, alkaloids, glycosides, flavonoids, steroids, fixed oils, and fats. Results: Pharmacological investigation included the analgesic activity using C. cretica (fruit) plant ethyl acetate extract when subjected to Eddy’s Hot Plate Model. The obtained results for analgesic activity of C. cretica (fruit) plant extract (ethyl acetate) (100 mg/kg and 200 mg/kg) were found positive

Keywords: Cressa cretica, fruit, screening
Mechanism of action and clinical effects of teeth whitening on enamel and dentin bonding for resin-based restorations

Mechanism of action and clinical effects of teeth whitening on enamel and dentin bonding for resin-based restorations

Authors: Karishma Vijan
Year: 2018, Volume: 5, Number: 1
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Abstract

The yellow, dull, and discolored permanent anterior teeth are a common esthetic dilemma and require competent solutions. This article deals with the mechanism and clinical effects of teeth whitening on enamel and dentin bonding efficacy.

Keywords:
The effect of acupressure applied to P6 acupuncture point on nausea, vomiting, and retching

The effect of acupressure applied to P6 acupuncture point on nausea, vomiting, and retching

Authors: Tulay Bulbul
Year: 2018, Volume: 5, Number: 1
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Abstract

Purpose: The research was carried out to determine the effect of acupressure applied to the P6 acupuncture point on nausea, vomiting, and retching among pregnant women with hyperemesis gravidarum. Methods: In the study, 64 were assigned to the control group and 64 to the intervention group. During their hospital stay, the pregnant women in the intervention group were given wristbands while the control group did not receive any application. Results: According to index of nausea, vomiting, and retching, the morning nausea scores of the intervention group were higher compared to evening nausea scores on the 1st day while the control group had higher morning nausea scores than evening nausea scores on the 1st and 2nd days. Conclusion: Acupressure applied to the P6 acupuncture point with a wristband did not completely eliminate nausea, vomiting, and retching caused by hyperemesis gravidarum, but it had a decreasing effect during certain periods of the day.

Keywords: Acupressure, hyperemesis, nausea, nursing, vomiting
Laparoscopic simple closure for perforated duodenal ulcer in young adults

Laparoscopic simple closure for perforated duodenal ulcer in young adults

Authors: Abdulrahman Saleh Al-Mulhim
Year: 2018, Volume: 5, Number: 1
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Abstract

Objective: Peptic ulcer perforation is one of the most common perforations of the gastrointestinal tract, and this complication of peptic ulcer is traditionally surgically treated. In recent years, a number of papers show a shift for perforation incidence from older to the younger population in developing countries. The aim of this study is to present the outcome of laparoscopic simple closure for perforated duodenal ulcer in young adults. Materials and Methods: Laparoscopic simple closure performs in 17 young patients (21–36 years) admitted as perforated duodenal ulcer from January 2014 to December 2016. Prospective analyses carry out of patient demographics, presentation, and clinical outcome. Results: This study consists of 17 patients between 21 and 36 years of age (mean of 26.9 years), and only 3 (17.6%) were females. Pain was the consistent symptom in all patients, while guarding was the signs present in all. No patients presented as shock but tachycardia noticed in those presented late. Pneumoperitoneum was found in all abdominal computed tomography scans. All underwent laparoscopic simple repair, and the mean post-operative follow-up was 15 months (8–34 months), and 13 patients (76%) come for a regular follow-up. Conclusion: Peptic ulcer perforation is a disease more common in the young population with a male preponderance in developing countries, and laparoscopic simple closure of perforated duodenal ulcer is safe and excellent outcome.

Keywords: Laparoscopic, perforated ulcer, simple
Riedel’s thyroiditis presenting as large retropharyngeal goiter - A rare case

Riedel’s thyroiditis presenting as large retropharyngeal goiter - A rare case

Authors: Bushra Khan
Year: 2018, Volume: 5, Number: 1
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Abstract

The thyroid gland lies in the anterior triangle of the neck in close approximation to the larynx and the trachea. The extension of an enlarged thyroid gland outside the normal confines of the thyroid bed is well known. A 35-year-old woman presented with a 12-year history of swelling in the midline of the neck which progressively increased in size and was currently associated with symptoms of dysphagia, difficulty in breathing, and hoarseness of voice. Physical examination revealed an ill-defined neck swelling moving on deglutition, with a bosselated surface with no overlying skin changes. Contrast-enhanced computed tomography scan of the neck revealed para- and retro-pharyngeal goiter with extension up to base of the tongue. Retropharyngeal extension of goiter is thought to be a rare entity in itself as shown in literature, but a large retropharyngeal goiter in Riedel’s thyroiditis has not been described before and seems to depend mainly on the body habitus of the patient.

Keywords: Fibrozing variant of Hashimoto’s thyroiditis, imaging, retropharyngeal goiter, Riedel’s thyroiditis

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