Asian Pacific Journal of Health Sciences

Asian Pacific Journal of Health Sciences

Basic info

  • Publisher: IJPMR Publishing Press, India.
  • Country of publisher: india
  • Date added to EuroPub: 2019/Sep/29

Subject and more

  • LCC Subject Category: Medicine, Health and Wellness
  • Publisher's keywords: Medicine, Health
  • Language of fulltext: english
  • Time from submission to publication: 6 weeks

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Open access & licensing

  • Type of License: CC BY
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 2014
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: Other
  • Deposit policy registered in: None

This journal has '459' articles

The Effect of Mode of Delivery on Breastfeeding Outcomes: A Hospital Based Study

The Effect of Mode of Delivery on Breastfeeding Outcomes: A Hospital Based Study

Authors: Anil C Mathew
Year: 2018, Volume: 5, Number: 3
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Abstract

Background: Some studies suggested that a high rate of caesarean deliveries results in suboptimal breastfeeding outcomes. The relationship between mode of delivery and breastfeeding outcomes has been considered important given the rising prevalence of caesarean deliveries globally. The present study is to examine the relationship of mode of delivery with breastfeeding outcomes. Materials and Methods: This study was conducted at PSG Institute of Medical Science and Research, Coimbatore in the month of July 2018. Ethical clearance was obtained from the institution prior to the study. Chi square test was done to assess the association between socio-demographic variables, timely initiation of breastfeeding and exclusive breastfeeding with mode of delivery. The effect of caesarean on duration of breastfeeding was obtained by applying Kaplan-Meier method. Result: Prevalence of caesarean delivery was 36.2% and of vaginal delivery was 63.8%. A statistically significant association was obtained between caesarean deliveries and timely initiation of breastfeeding. However mode of delivery was not significantly associated with exclusive breastfeeding and duration of breastfeeding. Conclusion: The findings of our study indicates that caesarean deliveries have been associated with lower timely initiation n rates compared to vaginal deliveries.

Keywords: caesarean delivery, duration of breast feeding, exclusive breastfeeding, initial breastfeeding, vaginal delivery.
Echocardiographic evaluation in systemic hypertension

Echocardiographic evaluation in systemic hypertension

Authors: Varun Kumar Perumalla
Year: 2018, Volume: 5, Number: 3
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Abstract

Echocardiography can detect cardiac morphologic and hemodynamic change caused by systemic arterial hypertension, echocardiography is a powerful tool for the evaluation of target organ damage, which is essential for the evaluation of cardiovascular risk. This study was conducted at Kamineni Institute of Medical Sciences, Narkatpally,Telangana State. The aim of this study was Echocardiographic evaluation of cardiac status in systemic hypertension patients. All patients of systemic hypertension whose diastolic blood pressure was persistently over 90mm Hg, were selected for study. This includes 50 hypertensive patients of age 30-60 years of both sexes. There were 33 males and 17 female. Hypertension was more common in mean age of 49 years, males are mostly effected than females. Left ventricular hypertrophy seen in 76% of patients, 58% of patients have diastolic dysfunction,6% patients have systolic dysfunction and 12% had both systolic and diastolic dysfunction. About 24% had no left ventricular dysfunction. Congestive heart failure was seen in 10% of patients, among them 4% with LV diastolic dysfunction, 2%systolic dysfunction and 4% with both dysfunctions were noticed.

Keywords: Echocardiography, systemic hypertension, left ventricular hypertrophy, Congestive heart failure, systolic dysfunction, diastolic dysfunction
Chronobiology and Chronotherapy for rheumatoid arhthritis

Chronobiology and Chronotherapy for rheumatoid arhthritis

Authors: Binu Raina
Year: 2018, Volume: 5, Number: 3
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Abstract

Pulsatile drug delivery systems have been a major field of research recently. It is the most interesting time-specific and site-specific system. This system is designed for chronopharmacotherapy which is based on circadian rhythm. This means these systems will deliver drug at the time when disease displays it's most morbid and mortal state within a circadian cycle. The use of these systems has been investigated on diseases like asthma, arthritis, ulcers, cardiovascular diseases, hypercholesterolemia, cancer etc. Various capsular, osmotic, single and multiple unit systems that are modulated by soluble or erodible polymer coatings, rupturable membranes are discussed in the article below.

Keywords: Pulsatile, circardian, delivery, drug
Treatment of Acute Apical Abscess by Endodontic Management

Treatment of Acute Apical Abscess by Endodontic Management

Authors: Dr. Akankshita Behera
Year: 2018, Volume: 5, Number: 3
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Abstract

Acute apical abscess is most common dental disease. It is formed when the infection from root canal travel to the periapical tissues followed by the formation of pus. A clinician must have a thorough idea about the management and regimens that is best given to treat the disease. The purpose of this article was to describe the endodontic management of an Acute Apical Abscess in an 21 year-old girl. The patient presented inflammation of extraoral tissues

Keywords: Acute Apical Abscess, Endodontic Management, Maxillary molar.
Pulsatile Drug Delivery System: A Review

Pulsatile Drug Delivery System: A Review

Authors: Abhimanyu Rai Sharma
Year: 2018, Volume: 5, Number: 3
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Abstract

Pulsatile drug delivery systems have been a major field of research recently. It is the most interesting time-specific and site-specific system. This system is designed for chronopharmacotherapy which is based on circadian rhythm. This means these systems will deliver drug at the time when disease displays it's most morbid and mortal state within a circadian cycle. The use of these systems has been investigated on diseases like asthma, arthritis, ulcers, cardiovascular diseases, hypercholesterolemia, cancer etc. Various capsular, osmotic, single and multiple unit systems that are modulated by soluble or erodible polymer coatings, rupturable membranes are discussed in the article below.

Keywords: Pulsatile, deliver, drug .
Emotional intelligence and clinical performance across practice areas: Implications for health professions educators and practitioners

Emotional intelligence and clinical performance across practice areas: Implications for health professions educators and practitioners

Authors: Lisa Gordon- Handler
Year: 2018, Volume: 5, Number: 3
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Abstract

Objective: The evaluation of student clinical competencies is multifactorial, with emotional intelligence (EI) considered as an essential component for success. Currently there is a lack of knowledge on whether distinct EI competencies are related to specific practice areas. This study purpose was to explore the relationship between supervisor’s perception of student EI and clinical performance across practice areas. Methods: This cross-sectional study utilized a sample of convenience to gather data from 52 full-time occupational therapy students and their respective supervisors at the completion of their clinical rotations. The Fieldwork Performance Evaluation (FWPE) and The Emotional and Social Competency Inventory-University version (ESCI-U) were used. A Pearson’s correlation coefficient analysis was used to explore the associations between EI competencies and clinical performance. Results: Higher EI scores were associated with higher scores on clinical performance during physical disability rotations. Findings show EI competencies of conflict management and self and organizational awareness to be associated with student ability to use clinical reasoning to deliver client-centered occupation-based goals, including proficiency of technical skills in a physical disabilities practice area. Conclusion: Findings provide additional support and suggestions for the context related role of EI in health profession clinical education.

Keywords: clinical education, emotional and social intelligence, health professions education.
Unconventional Biomarkers: Early ‘Snapshots’ of Cardiovascular risk in Young Overweight and Obese adults

Unconventional Biomarkers: Early ‘Snapshots’ of Cardiovascular risk in Young Overweight and Obese adults

Authors: Dr. Sourya Acharya
Year: 2018, Volume: 5, Number: 3
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Abstract

Background:Atherosclerosis of the coronary arteries leads to a restriction in coronary blood flow. Multiple studies have demonstrated that total leukocyte, monocyte and neutrophil counts are significantly higher in CAD patients. Serum uric acidhas also been found to be an independent risk factor for both cardiovascular and renal diseases.Looking at the dearth of data regarding association of these risk markers in overweight and obese young adults, this study was carried out.Aim and Objectives: To study the correlation of pro-inflammatory markers of development of coronary artery disease in overweight and obese young adults.Methodology: A prospective cross-sectional study was conducted in a rural Tertiary Care centre for a period of two months.Two hundred medical students acted as study participants, and were subdivided into healthy controls, and an overweight/obese group. Anthropometric data, haematological, and biochemical parameters were obtained, and correlated with respective groups.Statistical Analysis:Chi square test and Student ‘t’ Test were employed, with software used for the analysis being IBM SPSS Version 22.0, and p <0.05 being considered as significant.Results:Waist circumference and waist hip ratio (WHR) was significantly more in overweight and obese adults suggesting increased prevalence of visceral obesity. The monocyte percentage, neutrophil to lymphocyte ratio (NLR), and Serum uric acid levels were significantly elevated in overweight/obese category (p<0.05). Conclusion:The study demonstrated that overweight and obese young adults do have significantly increased levels of some unconventional biomarkers which can indicate future risk of cardiovascular diseases, and thus are indeed early “snapshots” which can be considered as warning signs. Early lifestyle modificationcan reduce the risk of cardiovascular disorders in such individuals.

Keywords: Coronary artery disease, Waist:Hip circumference, monocyte, Uric acid, lymphocyte, neutrophil.
A study of Occurrence of columnar cell lesions in neoplastic and non –neoplastic lesions of breast

A study of Occurrence of columnar cell lesions in neoplastic and non –neoplastic lesions of breast

Authors: Sunethri P
Year: 2018, Volume: 5, Number: 3
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Abstract

Background: Columnar cell lesions of breast are increasingly being encountered in breast biopsies because of their associated micro calcifications which are detected on mammographic screening.Observational studies suggest the co-existence of Columnar cell lesions with more advanced lesions of breast like Ductal carcinoma in situ,Atypical ductal hyperplasia and Invasive carcinoma. The presence of Columnar cell lesionneeds careful search for other atypical breast lesionsin proximity. Aim: To study the occurrence of Columnar cell lesions in Neoplastic and Non-Neoplastic breast lesions and evaluate the type of lesion with respect to category of breast lesion.Materials and methods: This is an observational study conducted in the Department of Pathology,Gandhi hospitalfrom January 2016 to December 2017.H&E stained sections of Neoplastic and Non-Neoplastic breast lesions were reviewed and associated Columnar cell changes were evaluated.Results:Total200 breast lesions were studiedout of which 134 showed Columnar cell lesions. 90% cases of fibrocystic disease and 60% of fibroadenoma cases were associated with CCL and the predominant type of lesionis Columnar cell change. 80% cases of Ductal carcinoma insituand 40% of Infiltrative duct cell carcinoma cases showed CCL and the common lesion is Columnar cell hyperplasia without atypia.Conclusion: Columnar cell lesions were observed in both Neoplastic and Non-Neoplastic breast lesions. Based on previous observational studies cancer risk associated with CCL is only mild on long term follow up. However detection of CCL in biopsy should prompt additional scrutiny for other pathological changes.

Keywords: Columnar cell lesion, Micro calcifications, Neoplastic and Non-Neoplastic breast lesions, Terminal duct lobular unit
Chondrosarcoma radiotherapy with helical delivery and analysis of MR guidance

Chondrosarcoma radiotherapy with helical delivery and analysis of MR guidance

Authors: Suresh Aggarwal
Year: 2018, Volume: 5, Number: 3
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Abstract

Purpose: To screen cell and metabolic qualities of chondrosarcoma of thoracic spine through the span of standard 6-week chemoradiation treatment on helical delivery with compound trade immersion exchange - MRI; and to recognize the most suitable process for CEST could decide consequent restorative reaction. Material and Methods: Twelve patients with recently analyzed chondrosarcoma were selected, and CEST-MRI was obtained promptly previously (Day0), 2 weeks (Day14) and a month (Day28) into treatment, and multi month after the finish of treatment (Day70). A few CEST measurements, including charge exchange proportion and region under the bend of CEST tops relating to atomic Overhauser impact and amide protons (MTRNOE, MTRAmide, CESTNOE, and CEST Amide separately), polarization exchange (MT), and direct water impact were examined. Normal tissue volume with target volume coverage was analyzed with plans yielding mean low dose. Absence of early movement was resolved as no expansion in tumor size or intensifying of clinical side effects as per routine post-chemoradiation serial auxiliary MRI. Results : Changes in MTRNOE (nonprogressors = 1.35 ± 0.18, progressors = 0.97 ± 0.22, P = .006) and MTRAmide (nonprogressors = 1.25 ± 0.17, progressors = 0.99 ± 0.10, P = .017) between pattern (Day0) and Day14 brought about the best detachment of nonprogressors from progressors. Besides, the pattern (Day0) MTRNOE (nonprogressors = 6.5% ± 1.6%, progressors = 9.1% ± 2.1%, P = .015), MTRAmide (nonprogressors = 6.7% ± 1.7%, progressors = 8.9% ± 1.9%, P = .028), MT (nonprogressors = 3.8% ± 0.9%, progressors = 5.4% ± 1.4%, P = .019), and CESTNOE (nonprogressors = 4.1%ċHz ± 1.7%ċHz, progressors = 6.1%ċHz ± 1.9%ċHz, P = .044) could distinguish progressors even before the beginning of the treatment.

Keywords: Chondrosarcoma, MRI, Treatment planning, CT, radiotherapy
Septic abortion leading to intestinal perforation: 4 case reports with Review of literature

Septic abortion leading to intestinal perforation: 4 case reports with Review of literature

Authors: Pushpendra Malik
Year: 2018, Volume: 5, Number: 3
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Abstract

Abortion is considered taboo In our society so it is unreasonable to expect reliable data about abortion practices , especially in India more so in rural areas . Most of illegal abortions are conducted in rural areas of developing countries without adequate facilities and person with no knowledge of anatomy who operate with non sterile instruments which further add to morbidity and mortality. As per the world Health Organization (WHO) estimate for 2000, about 19 million unsafe abortions performed worldwide resulting in death of 70000 women. Uterine perforation during abortion is rare, with incidence of 0.05-0.4 % but up to 3.6 % in undeveloped counties. One rare complication following surgical abortion is bowel perforation , small bowel is most commonly perforated due to central pelvic location, length and mobility . Illegal abortion are performed especially in unmarried females with secrecy. These abortions are performed at clinics run by quacks, dais and nurses with little knowledge of procedures and its outcomes, most of patients belong to low socioeconomic status and delayed referral mostly contribute to increased morbidity and mortality . Here we are presenting 4 cases which presented to our emergency ( Rural Tertiary care center BPS GMC Khanpur kalan) over a period of 3 months with perforation peritonitis after unsafe abortion.

Keywords: Septic Abortion, Intestinal Perforation, emergency laparotomy
Factors Associated with Timely Initiation of Breast Feeding: a Hospital Based Study

Factors Associated with Timely Initiation of Breast Feeding: a Hospital Based Study

Authors: Anil C Mathew
Year: 2018, Volume: 5, Number: 3
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Abstract

Background: Early or timely initiation of breastfeeding, specifically within 1 h of birth, refers to the best practice recommendation by the World Health Organization (WHO). Timely initiation of breastfeeding has the potential to prevent 22 % of neonatal deaths if all infants were breastfed within an hour after birth [1]. The primary objective of the paper is to estimate the prevalence of breast feeding initiation within first hour of life and the clinical correlates and socio demographic factors. Material and methods: This study was conducted at PSG Institute of Medical Science and Research, Coimbatore in the month of July 2018. Mothers with the children age below four years attending paediatric outpatient department were included in the study. Multivariate logistic analysis was usedto determine the factors associated with timely initiation breastfeeding practice. Results: The prevalence of timely initiation of breastfeeding within one hour was 56.5%. It was observed that the caesarean delivery, preterm delivery, sick condition of the baby, earlier breast surgery, lack of counselling after delivery and lack of skin to skin contact at birth were negatively associated with timely initiation of breastfeeding within one hour. Conclusion: The findings clearly indicated that nearly half of the mothers did not initiate breastfeeding within one hour of birth.

Keywords: breastfeeding, prevalence, sociodemographic factors, timely initiation.
Synthesis, Characterization and Antimicrobial evaluation of novel Azole Based (p-Toluic Acid) derivatives

Synthesis, Characterization and Antimicrobial evaluation of novel Azole Based (p-Toluic Acid) derivatives

Authors: Omprakash Sharma
Year: 2018, Volume: 5, Number: 3
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Abstract

This study includes the Synthesis of Azoles Based p-Toluic Acid Derivative. The compounds were prepared by reaction of p-Toluic Acid with thiosemicarbazide in the presence of Phosphorus oxychloride to yield 1, 3, 4-thiadiazole nucleus. Further this thiadiazole was treated with different aromatic aldehydes in presence of methanol to yield corresponding Schiff’s bases. All the Schiff’s bases thus obtained were reacted with Thioglycolic acid to yield the title compounds. Synthesized derivatives were characterized by IR, H1NMR and screened for their antibacterial (S. aureus, B. subtilis, E. coli, and P. aerugiosa) and antifungal activity (A. Niger and C. albicans).

Keywords: Azole derivative, p-Toluic Acid derivative, antimicrobial activity
Metastatic malignant melanoma from an unknown primary presenting as an axillary mass

Metastatic malignant melanoma from an unknown primary presenting as an axillary mass

Authors: Dr. Sonam Sharma
Year: 2018, Volume: 5, Number: 1
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Abstract

Malignant melanoma is a primary skin cancer, the incidence of which is rising at a faster rate than any other malignancy. Regional lymph nodes metastasis is seen in two-thirds of the patients of malignant melanoma. However, patients are also known to present with metastatic nodes in the absence of a known primary. The authors report a rare case of metastatic malignant melanoma from an unknown primary in a 62-year-old male who presented with an axillary mass.

Keywords: axillary mass, lymph node metastasis, melanoma, unknown primary
“C”-shaped root canal configuration in mandibular second molars: A case series

“C”-shaped root canal configuration in mandibular second molars: A case series

Authors: Vallari Jain
Year: 2018, Volume: 5, Number: 1
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Abstract

The C-shaped root canal configuration is an unusual variation encountered in mandibular second molars. One should be prepared and equipped to treat such unusual features when performing endodontic treatment. The present cases represent different C-shaped canal configurations on the basis of both the appearance of the canal orifices and the configuration along the roots. Use of cone-beam computed tomography, dental operating microscope, rotary and hand instrumentation assisted with sonic and ultrasonic activation of irrigants, and modified obturation techniques further aid in effective management of these anomalous canal configurations and ensure a threedimensional fill of the canal system.

Keywords: C-shaped root canal anatomy, mandibular second molar, root canal treatment
Hemophagocytic syndrome secondary to Plasmodium vivax infection - A prospective study of 11 cases

Hemophagocytic syndrome secondary to Plasmodium vivax infection - A prospective study of 11 cases

Authors: nupur rastogi
Year: 2018, Volume: 5, Number: 1
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Abstract

Background: Hemophagocytic syndrome is a reactive disorder of the mononuclear phagocytic system. The association of pancytopenia in severe malaria due to Plasmodium vivax with hemophagocytic syndrome is extremely rare and very few cases are reported in the world literature. Aim: The study was undertaken to establish P. vivax infestation associated with hemophagocytosis in bone marrow as one of the causes of chronic pancytopenia/bicytopenia with fever and splenomegaly in endemic areas. Materials and Methods: Prospective study of 110 patients of different age groups presenting with chronic fever with pancytopenia or bicytopenia from January 2015 to November 2017 was carried out. 49 patients showed the presence of P. vivax trophozoites in bone marrow. Among these 11 patients showed the presence of hemophagocytosis in bone marrow fulfilling 6 out of 8 criteria of diagnosing hemophagocytic lymphohistiocytosis according to 2004 criteria. Results: The age of patients varied from 8 years to 54 years. 11 Cases showed the presence of P. vivax trophozoites with the presence of hemophagocytosis in bone marrow showing, hyperplastic marrow showing normoblastic and megaloblastic hyperplasia. Conclusion: Hemophagocytic syndrome in malaria should be suspected in all cases of chronic fever with pancytopenia or bicytopenia, splenomegaly. Bone marrow aspiration is recommended to confirm the diagnosis of P. vivax as one of the causes of the secondary hemophagocytic syndrome in malaria-endemic areas.

Keywords: Bone marrow aspiration, hemophagocytosis, malaria

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