53 Study of comparative evaluation of bupivacaine and bupivacaine with dexmedetomidine in subarachnoid block for below umbilical surgeries Authors: Nitinkumar Ingle, Pradnya Hingole, Deepak kokane, Satish G Deshpande Year: 2017, Volume: 3, Number: 1 Medpulse International Journal of Anesthesiology 2019/Nov/09 (0 downloads) Abstract Background: Spinal anaesthesia is the most preferred regional anaesthesia technique as it is easy to perform, economical and produces rapid onset of anaesthesia and complete muscle relaxation. Dexmedetomidine, an α2 agonist drug providing stable hemodynamic conditions, good quality of intraoperative and prolonged postoperative analgesia with minimal side effects. Aim and Objective: To compare and evaluate bupivacaine and bupivacaine with dexmedetomidine in subarachnoid block for below umbilical surgeries. Material and Methods: It was prospective, randomized, double blind study conducted at tertiary care centre over a period extending from January 2014 to October 2015. The study included a total of 100 patients divided into two groups (each of 50 patients) i.e. control and study groups depending upon drugs administered. Results: The onset of sensory block as well as time for attaining maximum sensory level was significantly faster (p < 0.05) in study group as compared to control group. Also, regression of sensory block was slower and onset of motor block is quicker in patients those who received intrathecal dexmedetomidine. There was a significant prolonged duration of sensory analgesia among study group. Summary and Conclusions: Use of0.5% hyperbaric Bupivacaine (15mg) with dexmedetomidine (5mcg) in subarachnoid block Leads to significantly quicker onset of Motor and Sensory block also a minimal intraoperative and postoperative complication as compared to 0.5% hyperbaric Bupivacaine Keywords: bupivacaine, dexmedetomidine.