Antibody Drug Conjugates: Application of Quantitative Pharmacology in Modality Design and Target Selection Journal title: The AAPS Journal Authors: S. Sadekar, I. Figueroa, M. Tabrizi Subject(s): Medicine
Antibody Drug Conjugates: Nonclinical Safety Considerations Journal title: The AAPS Journal Authors: Mary Jane Masson Hinrichs, Rakesh Dixit Subject(s): Medicine
Marketplace Analysis of Conjugated Estrogens: Determining the Consistently Present Steroidal Content with LC-MS Journal title: The AAPS Journal Authors: Michaella J. Levy, Michael T. Boyne, II, Sarah Rogstad, David J. Skanchy, Xiaohui Jiang, Ilan Geerlo... Subject(s): Medicine
Analyzing Subvisible Particles in Protein Drug Products: a Comparison of Dynamic Light Scattering (DLS) and Resonant Mass Measurement (RMM) Journal title: The AAPS Journal Authors: Jainik Panchal, Joseph Kotarek, Ewa Marszal, Elizabeth M. Topp Subject(s): Medicine
A Priori Prediction of Tumor Payload Concentrations: Preclinical Case Study with an Auristatin-Based Anti-5T4 Antibody-Drug Conjugate Journal title: The AAPS Journal Authors: Dhaval K. Shah, Lindsay E. King, Xiaogang Han, Jo-Ann Wentland, Yanhua Zhang, Judy Lucas, Nahor Hadd... Subject(s): Medicine
Role of Metabolism in the Effects of Genistein and Its Phase II Conjugates on the Growth of Human Breast Cell Lines Journal title: The AAPS Journal Authors: Bo Yuan, Linglan Wang, Yi Jin, Huijuan Zhen, Pingwei Xu, Youjun Xu, Chibing Li, Haiyan Xu Subject(s): Medicine
ADME of Antibody–Maytansinoid Conjugates Journal title: The AAPS Journal Authors: Hans K. Erickson, John M. Lambert Subject(s): Medicine
The Coulter Principle for Analysis of Subvisible Particles in Protein Formulations Journal title: The AAPS Journal Authors: Matthew N. Rhyner Subject(s): Medicine
Polymer-drug conjugates as modulators of cellular apoptosis Journal title: The AAPS Journal Authors: Maria J. Vicent Subject(s): Medicine
A Bayesian Approach for Quantifying Trace Amounts of Antibody Aggregates by Sedimentation Velocity Analytical Ultracentrifugation Journal title: The AAPS Journal Authors: Patrick H. Brown, Andrea Balbo, Peter Schuck Subject(s): Medicine
Blood pressure as an example of a biomarker that functions as a surrogate Journal title: The AAPS Journal Authors: Mehul Desai, Norman Stockbridge, Robert Temple Subject(s): Medicine
A Mechanistic Pharmacokinetic Model Elucidating the Disposition of Trastuzumab Emtansine (T-DM1), an Antibody–Drug Conjugate (ADC) for Treatment of Metastatic Breast Cancer Journal title: The AAPS Journal Authors: Brendan Bender, Douglas D. Leipold, Keyang Xu, Ben-Quan Shen, Jay Tibbitts, Lena E. Friberg Subject(s): Medicine
Effects of protein aggregates: An immunologic perspective Journal title: The AAPS Journal Authors: Amy S. Rosenberg Subject(s): Medicine
Is any measurement method optimal for all aggregate sizes and types? Journal title: The AAPS Journal Authors: John S. Philo Subject(s): Medicine
A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation Journal title: The AAPS Journal Authors: Jun Liu, James D. Andya, Steven J. Shire Subject(s): Medicine
